PEDIATRICS Vol. 18 No. 2 August 1956, pp. 167-176
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STUDIES OF CARBOHYDRATE METABOLISM IN THE NEWBORN

I. Capillary-venous Differences in Blood Sugar in Normal Newborn Infants

Marvin Cornblath M.D.1, Ephraim Y. Levin 1, and Harry H. Gordon M.D.1

1 Departments of Pediatrics of Sinai Hospital of Baltimore, and Johns Hopkins Medical Institutions

Capillary-venous differences in concentrations of blood sugar were measured in 55 newborn infants during the first 15 hours of life. The capillary-venous difference is related to the capillary level under fasting conditions. The administration of glucose by gavage in doses of 2 to 3 gm./kg. led to a prompt rise in concentration of glucose in capillary blood and an increase in capillary-venous difference. The administration of .03 µg./kg. of epinephrine led to a prompt increase in concentration of glucose in capillary blood but to a decrease in the capillary-venous difference.

The relation of these findings to homeostatic mechanisms in the newborn was discussed.

Submitted on January 30, 1956
Accepted on February 17, 1956