1 Department of Pediatrics, Harvard Medical School, Boston Lying-In Hospital, Beth Israel Hospital, and Joslin Clinic, Boston
Data has been presented to show that the respiratory rates of infants of diabetic mothers are significantly higher than those of normal full-term infants. [SEE TABLE VI IN SOURCE PDF].
Although the respiratory rates of premature infants and normal infants delivered by cesarean section are slightly higher than those of normal full-term infants, they are insufficient to account for the marked increase of respiratory rates in infants of diabetic mothers. The high incidence of pulmonary hyaline membranes in these infants appears to be the most likely explanation for the elevated respiratory rates.
Cortisone does not appear to materially affect the respiratory distress nor the respiratory rates in infants of diabetic mothers.
Although the results obtained in the present study do not directly clarify either the etiology nor the mechanism for formation of hyaline membranes in infants of diabetic mothers, the simple measurement of respiratory rates does provide an objective means for evaluating therapy in controlled trials.
Submitted on August 8, 1955
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