PEDIATRICS Vol. 14 No. 5 November 1954, pp. 481-494
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COCCIDIOIDOMYCOSIS IN CHILDREN

JAMES L. DENNIS M.D.1 and ARILD E. HANSEN M.D., PH.D.1

1 The Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas.

1. The pediatric implications of coccidioidomycosis have been presented including the clinical features as well as the specific diagnostic procedures. 2. The in vitro response of coccidioides immites to ethyl vanillate, para-aminobenzoic acid and Thiocymetin have been reported. The direct observation of the effect of drugs upon spherules in living tissue cultures has been made with some degree of success. 3. Four children with disseminated coccidioidomycosis have been used to illustrate the clinical and serologic responses to various drugs. 4. At this time ethyl vanillate appears to be the best agent available. Although in selective cases actual cure seems possible, the occasional spontaneous regression of the disseminated disease demands caution in the evaluation of any chemotherapeutic agent.




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V. J. Gururaj, W. W. Marsh, and S. R. Aiyar
Fulminant Pulmonary Coccidioidomycosis in Association with Coxsackie B4 Infection
Clinical Pediatrics, July 1, 1985; 24(7): 406 - 408.
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