PEDIATRICS Vol. 14 No. 4 October 1954, pp. 346-350
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by JONES, M. H.
Right arrow Articles by KOCH, F. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by JONES, M. H.
Right arrow Articles by KOCH, F. P.

LONGITUDINAL STUDY OF THE INCIDENCE OF CENTRAL NERVOUS SYSTEM DAMAGE FOLLOWING ERYTHROBLASTOSIS FETALIS

MARGARET H. JONES M.D.1, RUSSELL SANDS M.D.1, CAROL B. HYMAN M.D.1, PHILLIP STURGEON M.D.2, and FREMONT P. KOCH M.D.1

1 The Childrens Hospital, Los Angeles, and the Department of Pediatrics, University of Southern California School of Medicine, Los Angeles.
2 The Childrens Hospital, Los Angeles, and the Department of Pediatrics, University of Southern California School of Medicine, Los Angeles., Markle Scholar in Medical Sciences.

One hundred unselected cases of erythroblastosis fetalis treated at Childrens Hospital in the newborn period have been followed from six months to five years in an effort to evaluate the relation of central nervous system signs in the newborn period to neuromuscular handicap and overall development later.

Of those showing no central nervous system signs in the newborn period 4% showed definite abnormality later.

Of those showing equivocal signs in the newborn period 33% showed definite abnormality later.

Of those having definite signs early, 100% continued to show abnormality in infancy and childhood.

There was no relation of the severity of the signs in the newborn period to the severity of the later handicap.

It is suggested, therefore, that one cannot be certain of the later normality of an infant showing no definite or equivocal central nervous system involvement in the newborn period. Careful following of all erythroblastotic infants until six to eight years of age or longer is advisable.

Submitted on May 10, 1954




This article has been cited by other articles:


Home page
 PediatricsHome page
Subcommittee on Hyperbilirubinemia
Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation
Pediatrics, July 1, 2004; 114(1): 297 - 316.
[Abstract] [Full Text] [PDF]