PEDIATRICS Vol. 13 No. 5 May 1954, pp. 412-418
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STUDIES OF SERUM ELECTROLYTE CHANGES DURING EXCHANGE TRANSFUSION

GERALD MILLER M.D.1, AUGUSTA B. MCCOORD PH.D.1, HOWARD A. JOOS M.D.1, and SAMUEL W. CLAUSEN M.D.1

1 The Departments of Pediatrics and Medicine of the University of Rochester School of Medicine and Dentistry and the Strong Memorial and Rochester Municipal Hospitals, Rochester, N.Y.

Alterations in concentrations of serum potassium are reported in infants studied during exchange transfusion therapy for erythroblastosis. The elevated plasma potassium content of citrated whole blood following prolonged storage may produce hyperkaliemia in some infants. The authors have suggested that hypocalcemia and hyperkaliemia may coexist in some of these babies during exchange transfusion. Certain implications regarding the cumulative effects of these two disturbances are discussed in relation to exchange transfusion.

Submitted on October 11, 1953