PEDIATRICS Vol. 123 Supplement March 2009, pp. S160-S167 (doi:10.1542/peds.2008-2233F)
SUPPLEMENT ARTICLE |
Complex Interactions of Pollutant and Allergen Exposures and Their Impact on People With Asthma
Department of Pediatrics, Division of Allergy and Immunology, Johns Hopkins University, Baltimore, Maryland
Pediatric asthma has many causes and can manifest differently in different children and at different times. Understanding the many factors related to the development and exacerbation of asthma is complicated by the complexity of the many environmental exposures related to asthma development and morbidity. Furthermore, the same environmental exposures that may cause increased symptoms at 1 point in time may be protective when the exposure occurs earlier or at high enough levels. We know that environmental exposures such as allergens, irritants, and pollutants are quite complex in their composition; further examination of this complexity may improve our understanding of this complex and highly prevalent disease.
Key Words: asthma allergy pollutants
Abbreviations: DEP—diesel exhaust particle ETS—environmental tobacco smoke HEPA—high-efficiency particulate air IgE—immunoglobulin E PAMP—pathogen-associated molecular pattern TLR—Toll-like receptor Th—T helper
Accepted Nov 4, 2008.
![]()
CiteULike
Connotea
Del.icio.us
Digg
Facebook
Reddit
Technorati
Twitter What's this?
This article has been cited by other articles:
![]() |
N. Lurie, H. E. Mitchell, and F. J. Malveaux State of Childhood Asthma and Future Directions Conference: Overview and Commentary Pediatrics, March 1, 2009; 123(Supplement_3): S211 - S214. [Abstract] [Full Text] [PDF] |
||||





