Published online March 30, 2009
PEDIATRICS Vol. 123 No. 4 April 2009, pp. 1223-1228 (doi:10.1542/peds.2008-2381)
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SPECIAL ARTICLE

Screening and Treatment for Major Depressive Disorder in Children and Adolescents: US Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force

DESCRIPTION. This is an update of the 2002 US Preventive Services Task Force recommendation on screening for child and adolescent major depressive disorder.

METHODS. The US Preventive Services Task Force weighed the benefits and harms of screening and treatment for major depressive disorder in children and adolescents, incorporating new evidence addressing gaps in the 2002 recommendation statement. Evidence examined included the benefits and harms of screening, the accuracy of primary care–feasible screening tests, and the benefits and risks of treating depression by using psychotherapy and/or medications in patients aged 7 to 18 years.

RECOMMENDATIONS. Screen adolescents (12–18 years of age) for major depressive disorder when systems are in place to ensure accurate diagnosis, psychotherapy (cognitive-behavioral or interpersonal), and follow-up (B recommendation). Evidence is insufficient to warrant a recommendation to screen children (7–11 years of age) for major depressive disorder (I statement).

Key Words: screening • treatment • depression • child and adolescent

Abbreviations: USPSTF—US Preventive Services Task Force • MDD—major depressive disorder • SSRI—selective serotonin reuptake inhibitor • PHQ-A—Patient Health Questionnaire for Adolescents • BDI-PC—Beck Depression Inventory-Primary Care Version • RCT—randomized, controlled trial • CI—confidence interval

Accepted Aug 7, 2008.


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