Published online August 1, 2008
PEDIATRICS Vol. 122 No. 2 August 2008, pp. 398-417 (doi:10.1542/10.1542/peds.2007-1894)
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow View responses
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Misra, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Misra, M.
Related Collections
Right arrow Nutrition & Metabolism
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

STATE-OF-THE-ART REVIEW ARTICLE

Vitamin D Deficiency in Children and Its Management: Review of Current Knowledge and Recommendations

Madhusmita Misra, MD, MPHa, Danièle Pacaud, MDb, Anna Petryk, MDc, Paulo Ferrez Collett-Solberg, MDd, Michael Kappy, MD, PhDe on behalf of the Drug and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society

a Pediatric Endocrine and Neuroendocrine Units, Massachusetts General Hospital, Boston, Massachusetts
b Division of Pediatric Endocrinology, Department of Pediatrics, University of Calgary, Alberta Children's Hospital, Calgary, Alberta, Canada
c Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota
d Instituto Estadual de Diabetes e Endocrinologia, Rio de Janeiro, Brazil
e Children's Hospital Association, University of Colorado Health Sciences Center, Denver, Colorado

ABSTRACT

Given the recent spate of reports of vitamin D deficiency, there is a need to reexamine our understanding of natural and other sources of vitamin D, as well as mechanisms whereby vitamin D synthesis and intake can be optimized. This state-of-the-art report from the Drug and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society was aimed to perform this task and also reviews recommendations for sun exposure and vitamin D intake and possible caveats associated with these recommendations.

Key Words: food fortification • breastfeeding • calcium • supplements • vitamin D

Abbreviations: AAP—American Academy of Pediatrics • 25(OH)-D—25(OH)-vitamin D • UVR—ultraviolet radiation • PTH—parathyroid hormone • 1,25(OH)2-D—1,25-dihydroxy vitamin D • ALP—alkaline phosphatase • DBP—vitamin D–binding protein • 24,25(OH)2-D—24,25-dihydroxy vitamin D • MED—minimum erythema dose • mAb—monoclonal antibody • HPLC—high-pressure liquid chromatography • SPF—sun protection factor

Accepted Nov 26, 2007.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 J. Clin. Endocrinol. Metab.Home page
L. K. Bachrach and L. M. Ward
Clinical Review: Bisphosphonate Use in Childhood Osteoporosis
J. Clin. Endocrinol. Metab., February 1, 2009; 94(2): 400 - 409.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
C. L. Wagner, F. R. Greer, and and the Section on Breastfeeding and Committee on
Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents
Pediatrics, November 1, 2008; 122(5): 1142 - 1152.
[Abstract] [Full Text] [PDF]

eLetters:

Read all eLetters

Hypocalcemia due to vitamin D deficiency: is calcitriol treatment really required?
Giampiero I. Baroncelli, et al.
Pediatrics Online, 19 Mar 2009 [Full text]
Hypocalcemia due to vitamin D deficiency: is calcitriol treatment really required?
Giampiero I. Baroncelli, et al.
Pediatrics Online, 23 Apr 2009 [Full text]