Published online May 1, 2008
PEDIATRICS Vol. 121 No. 5 May 2008, pp. e1434-e1437 (doi:10.1542/peds.2007-1750)
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EXPERIENCE & REASON

Tuberculosis Mimicking Ileocecal Intussusception in a 5-Month-Old Girl

Jurriaan E. M. de Steenwinkel, MD, MSca, Gert-Jan A. Driessen, MDb, Margreet H. Kamphorst-Roemer, MD, MPHc, Antoine G. M. Zeegers, MDd, Alewijn Ott, MD, PhDa and Mireille van Westreenen, MD, PhDa

a Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Centre, Rotterdam, Netherlands
b Department of Paediatric Infectious Diseases, Erasmus MC, University Medical Centre, Rotterdam, Netherlands
c Subdivision Tuberculosis Control, Municipal Health Service, Rotterdam, Netherlands
d Department of Urology, Albert Schweitzer Hospital, Dordrecht, Netherlands

ABSTRACT

A 5-month-old girl was diagnosed with tuberculosis, mimicking ileocecal intussusception. The mother of the patient was later diagnosed with renal tuberculosis attributable to the same (unique) Mycobacterium tuberculosis strain. Possibly, that transmission occurred by aspiration or ingestion of infected amniotic fluid or urine, which could occur before or during birth. This case illustrates that tuberculosis can mimic other common diseases and, therefore, can be a difficult diagnosis to make. Because respiratory infection was very unlikely in this case, congenital tuberculosis or postnatal infection via infected urine or breast milk should be in the differential diagnosis. In this article, we focus on different (nonrespiratory) transmission routes of Mycobacterium tuberculosis and give a short review of the recent literature on congenital tuberculosis.

Key Words: tuberculosis • mycobacterium • diagnosis • urogenital tuberculosis • congenital tuberculosis

Abbreviations: MTB, Mycobacterium tuberculosis • TB, tuberculosis • CTB, congenital TB • CT, computed tomography • TST, tuberculin skin test • RFLP, restriction fragment length polymorphism

Accepted Oct 1, 2007.


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