Published online August 31, 2007
PEDIATRICS Vol. 120 No. 3 September 2007, pp. 609-616 (doi:10.1542/peds.2007-0336)
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (17)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Raju, T. N.K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Raju, T. N.K.
Related Collections
Right arrow Neurology & Psychiatry
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

SPECIAL ARTICLE

Ischemic Perinatal Stroke: Summary of a Workshop Sponsored by the National Institute of Child Health and Human Development and the National Institute of Neurological Disorders and Stroke

Tonse N.K. Raju, MD, DCHa, Karin B. Nelson, MDb, Donna Ferriero, MDc, John Kylan Lynch, DO, MPHb and the NICHD-NINDS Perinatal Stroke Workshop Participants

a National Institute of Child Health and Human Development
b National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
c Departments of Neurology and Pediatrics, University of California, San Francisco, California

Ischemic perinatal stroke is a disorder associated with significant long-term neurologic morbidity. With an estimated incidence of 1 in 2300 to 5000 births, stroke is more likely to occur in the perinatal period than at any time in childhood. The incidence of ischemic perinatal stroke ranks second only to that of strokes in the elderly population. Although ischemic perinatal stroke is a well-recognized disorder, many aspects remain to be studied. There is no consensus on its terminology, definition, or classification. Several risk factors have been identified, but their precise roles in causing stroke are not well understood. There are no reliable predictors of ischemic perinatal stroke on which to base prevention or treatment strategies. To review these important issues and propose a research agenda, the National Institute of Child Health and Human Development and the National Institute of Neurological Disorders and Stroke convened a workshop in August 2006. This article provides a summary of the workshop.

Key Words: cerebral palsy • diseases of pregnancy • focal cerebral infarction • congenital hemiplegia • hypoxic ischemic encephalopathy • intracranial hemorrhage • newborn • porencephaly • seizures • thrombotic disorders

Abbreviations: IPS—ischemic perinatal stroke • CP—cerebral palsy • MCA—middle cerebral artery • NICHD—National Institute of Child Health and Human Development • NINDS—National Institute of Neurological Disorders and Stroke • PPIS—presumed perinatal ischemic stroke • CT—computed tomography • DWI—diffusion-weighted imaging

Accepted Apr 11, 2007.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 J Child NeurolHome page
L. Slaughter, J. Egelhoff, and T. Balmakund
Neurologic Outcome in Neonatal Temporal Lobe Hemorrhagic Venous Infarcts
J Child Neurol, October 1, 2009; 24(10): 1236 - 1242.
[Abstract] [PDF]

Home page
 BrainHome page
A. O. Ballantyne, A. M. Spilkin, J. Hesselink, and D. A. Trauner
Plasticity in the developing brain: intellectual, language and academic functions in children with ischaemic perinatal stroke
Brain, November 1, 2008; 131(11): 2975 - 2985.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
C. S. Gibson, A. H. MacLennan, G. A. Dekker, P. N. Goldwater, T. R. Sullivan, D. J. Munroe, S. Tsang, C. Stewart, and K. B. Nelson
Candidate Genes and Cerebral Palsy: A Population-Based Study
Pediatrics, November 1, 2008; 122(5): 1079 - 1085.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
P. Monagle, E. Chalmers, A. Chan, G. deVeber, F. Kirkham, P. Massicotte, and A. D. Michelson
Antithrombotic Therapy in Neonates and Children: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)
Chest, June 1, 2008; 133(6_suppl): 887S - 968S.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
R. W. Redline, P. Sagar, M. E. King, K. S. Krishnamoorthy, E. F. Grabowski, and D. J. Roberts
Case 12-2008 -- A Newborn Infant with Intermittent Apnea and Seizures
N. Engl. J. Med., April 17, 2008; 358(16): 1713 - 1723.
[Full Text] [PDF]