PEDIATRICS Vol. 12 No. 4 October 1953, pp. 368-376
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by SILVER, H. K.
Right arrow Articles by DEAMER, W. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by SILVER, H. K.
Right arrow Articles by DEAMER, W. C.
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

SYNDROME OF CONGENITAL HEMIHYPERTROPHY, SHORTNESS OF STATURE, AND ELEVATED URINARY GONADOTROPINS

HENRY K. SILVER M.D.1, WILLIAM KIYASU M.D.2, JACK GEORGE M.D.3, and WILLIAM C. DEAMER M.D.4

1 The Department of Pediatrics, Yale University School of Medicine, New Haven.
2 The Department of Pediatrics, University of California School of Medicine, San Francisco.
3 Children's Hospital, Boston.
4 Children's Hospital, Philadelphia.

Two cases of a syndrome of hemihypertrophy, shortness of stature, and elevated levels of urinary gonadotropins are reported. One of the children was a male, the other a female.

The hemihypertrophy and shortness of stature had been present since birth and the elevated gonadotropins were found at 5frac12 and 6 years, respectively.

The possible relationship to other conditions in childhood including those which also have increased gonadotropins is discussed.

Submitted on May 23, 1953


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
J. Clin. Endocrinol. Metab.Home page
S. Bruce, K. Hannula-Jouppi, J. Peltonen, J. Kere, and M. Lipsanen-Nyman
Clinically Distinct Epigenetic Subgroups in Silver-Russell Syndrome: The Degree of H19 Hypomethylation Associates with Phenotype Severity and Genital and Skeletal Anomalies
J. Clin. Endocrinol. Metab., February 1, 2009; 94(2): 579 - 587.
[Abstract] [Full Text] [PDF]


Home page
J. Med. Genet.Home page
S Abu-Amero, D Monk, J Frost, M Preece, P Stanier, and G E Moore
The genetic aetiology of Silver-Russell syndrome
J. Med. Genet., April 1, 2008; 45(4): 193 - 199.
[Abstract] [Full Text] [PDF]


Home page
J. Clin. Endocrinol. Metab.Home page
I. Netchine, S. Rossignol, M.-N. Dufourg, S. Azzi, A. Rousseau, L. Perin, M. Houang, V. Steunou, B. Esteva, N. Thibaud, et al.
11p15 Imprinting Center Region 1 Loss of Methylation Is a Common and Specific Cause of Typical Russell-Silver Syndrome: Clinical Scoring System and Epigenetic-Phenotypic Correlations
J. Clin. Endocrinol. Metab., August 1, 2007; 92(8): 3148 - 3154.
[Abstract] [Full Text] [PDF]


Home page
J. Med. Genet.Home page
E Meyer, H A Wollmann, and T Eggermann
Searching for genomic variants in the MESTIT1 transcript in Silver-Russell syndrome patients
J. Med. Genet., May 1, 2003; 40(5): e65 - 65.
[Full Text] [PDF]


Home page
J. Med. Genet.Home page
L Bentley, K Nakabayashi, D Monk, C Beechey, J Peters, Z Birjandi, F E Khayat, M Patel, M A Preece, P Stanier, et al.
The imprinted region on human chromosome 7q32 extends to the carboxypeptidase A gene cluster: an imprinted candidate for Silver-Russell syndrome
J. Med. Genet., April 1, 2003; 40(4): 249 - 256.
[Abstract] [Full Text] [PDF]


Home page
J. Med. Genet.Home page
M P Hitchins, S Abu-Amero, S Apostolidou, D Monk, P Stanier, M A Preece, and G E Moore
Investigation of the GRB2, GRB7, and CSH1 genes as candidates for the Silver-Russell syndrome (SRS) on chromosome 17q
J. Med. Genet., March 1, 2002; 39(3): e13 - 13.
[Full Text] [PDF]


Home page
J. Med. Genet.Home page
M. P Hitchins, P. Stanier, M. A Preece, and G. E Moore
Silver-Russell syndrome: a dissection of the genetic aetiology and candidate chromosomal regions
J. Med. Genet., December 1, 2001; 38(12): 810 - 819.
[Abstract] [Full Text] [PDF]


Home page
Hum ReprodHome page
O. Ozturk, K. Armstrong, S. Bhattacharya, and A. Templeton
Fetal antecedents of male factor sub-fertility: how important is birthweight?
Hum. Reprod., October 1, 2001; 16(10): 2238 - 2241.
[Abstract] [Full Text] [PDF]


Home page
J. Med. Genet.Home page
K. HANNULA, J. KERE, S. PIRINEN, C. HOLMBERG, and M. LIPSANEN-NYMAN
Do patients with maternal uniparental disomy for chromosome 7 have a distinct mild Silver-Russell phenotype?
J. Med. Genet., April 1, 2001; 38(4): 273 - 278.
[Full Text]


Home page
J. Med. Genet.Home page
D. MONK, M. HITCHINS, S. RUSSO, M. PREECE, P. STANIER, and G. E MOORE
No evidence for mosaicism in Silver-Russell syndrome
J. Med. Genet., April 1, 2001; 38(4): 11e - 11.
[Full Text]


Home page
J. Med. Genet.Home page
E. L WAKELING, M. P HITCHINS, S. N ABU-AMERO, P. STANIER, G. E MOORE, and M. A PREECE
Biallelic expression of IGFBP1 and IGFBP3, two candidate genes for the Silver-Russell syndrome
J. Med. Genet., January 1, 2000; 37(1): 65 - 67.
[Full Text]


Home page
J. Med. Genet.Home page
S M Price, R Stanhope, C Garrett, M A Preece, and R C Trembath
The spectrum of Silver-Russell syndrome: a clinical and molecular genetic study and new diagnostic criteria
J. Med. Genet., November 1, 1999; 36(11): 837 - 842.
[Abstract] [Full Text]


Home page
J. Clin. Endocrinol. Metab.Home page
F. de Zegher, M. V. L. Du Caju, C. Heinrichs, M. Maes, J. De Schepper, M. Craen, K. Vanweser, P. Malvaux, and R. G. Rosenfeld
Early, Discontinuous, High Dose Growth Hormone Treatment to Normalize Height and Weight of Short Children Born Small for Gestational Age: Results Over 6 Years
J. Clin. Endocrinol. Metab., May 1, 1999; 84(5): 1558 - 1561.
[Abstract] [Full Text]


Home page
J Hand Surg Eur VolHome page
S. MAHMUD, K. NAMBA, K. SAMESHIMA, Y. NAKASHIMA, and R. NISHINO
Cleft Hand in Silver-Russell Syndrome
J Hand Surg Eur Vol., April 1, 1988; 13(2): 192 - 194.
[Abstract] [PDF]


Home page
Arch Pediatr Adolesc MedHome page
S. B. Cassidy, O. Blonder, V. W. Courtney, S. K. Ratzan, and D. E. Carey
Russell-Silver Syndrome and Hypopituitarism: Patient Report and Literature Review
Arch Pediatr Adolesc Med, February 1, 1986; 140(2): 155 - 159.
[Abstract] [PDF]


Home page
Arch Pediatr Adolesc MedHome page
L. J. Marks and P. S. Bergeson
The Silver-Russell Syndrome: A Case With Sexual Ambiguity, and a Review of the Literature
Arch Pediatr Adolesc Med, April 1, 1977; 131(4): 447 - 451.
[Abstract] [PDF]


Home page
Arch Pediatr Adolesc MedHome page
R. V. McDowell and E. T. Sproles III
The Russell-Silver Syndrome: A Nine-Year Follow-Up
Arch Pediatr Adolesc Med, December 1, 1973; 126(6): 794 - 796.
[Abstract] [PDF]


Home page
Arch Pediatr Adolesc MedHome page
L. M. Taussig, G. D. Braunstein, B. J. White, and R. L. Christiansen
Silver-Russell Dwarfism and Cystic Fibrosis in a Twin: Endocrine, Chromosomal, Dermatoglyphic, and Craniofacial Studies
Arch Pediatr Adolesc Med, April 1, 1973; 125(4): 495 - 503.
[Abstract] [PDF]


Home page
Arch Pediatr Adolesc MedHome page
M. E. Jenkins, J. Eisen, and F. Sequin
Congenital Asymmetry and Diploid-Triploid Mosaicism
Arch Pediatr Adolesc Med, July 1, 1971; 122(1): 80 - 84.
[Abstract] [PDF]


Home page
Arch DermatolHome page
S. Hurwitz and S. N. Klaus
Congenital Hemihypertrophy With Hypertrichosis
Arch Dermatol, January 1, 1971; 103(1): 98 - 100.
[Abstract] [PDF]


Home page
CLIN PEDIATRHome page
D. Sami
Two Examples of Silver's Syndrome
Clinical Pediatrics, October 1, 1969; 8(10): 602 - 603.
[PDF]


Home page
Arch Pediatr Adolesc MedHome page
J. F. J. Curi, R. C. Vanucci, H. Grossman, and M. New
Elevated Serum Gonadotrophins in Silver's Syndrome
Arch Pediatr Adolesc Med, December 1, 1967; 114(6): 658 - 661.
[Abstract] [PDF]


Home page
Arch Pediatr Adolesc MedHome page
H. K. SILVER
Asymmetry, Short Stature, and Variations in Sexual Development: A Syndrome of Congenital Malformations
Arch Pediatr Adolesc Med, May 1, 1964; 107(5): 495 - 515.
[Abstract] [PDF]


Home page
Arch Pediatr Adolesc MedHome page
H. C. REISTER and R. G. SCHERZ
Silver Syndrome: A Report of Two Cases and a Review of the Literature
Arch Pediatr Adolesc Med, April 1, 1964; 107(4): 410 - 416.
[Abstract] [PDF]


Home page
Arch Pediatr Adolesc MedHome page
S. STOOL and P. COHEN
Silver's Syndrome: Syndrome of Congenital Asymmetry, Short Stature, and Altered Pattern of Sexual Development
Arch Pediatr Adolesc Med, February 1, 1963; 105(2): 199 - 203.
[Abstract] [PDF]


Home page
Arch Pediatr Adolesc MedHome page
H. K. SILVER
Congenital Asymmetry, Short Stature, and Elevated Urinary Gonadotropin
Arch Pediatr Adolesc Med, June 1, 1959; 97(6): 768 - 773.
[Abstract] [PDF]


Home page
Arch Pediatr Adolesc MedHome page
H. K. SILVER and F. L. GRUSKAY
Syndrome of Congenital Hemihypertrophy and Elevated Urinary Gonadotropins: Occurrence in a Seven-Year-Old Boy
Arch Pediatr Adolesc Med, May 1, 1957; 93(5): 559 - 562.
[Abstract] [PDF]