PEDIATRICS Vol. 12 No. 2 August 1953, pp. 151-157
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STUDIES OF THE IMMUNOLOGY OF THE NEWBORN INFANT

IV. Antibody Formation in the Premature Infant

JOSEPH DANCIS M.D.1, JOHN J. OSBORN M.D.1, and HANS W. KUNZ M.D.2

1 The Department of Pediatrics, New York University College of Medicine, and the Pediatric Service of Bellevue Hospital, New York City., Fellow of The National Foundation for Infantile Paralysis.
2 The Department of Pediatrics, New York University College of Medicine, and the Pediatric Service of Bellevue Hospital, New York City.

The antibody response of premature infants immunized at birth with a single injection of diphtheria toxoid was compared to that of a group of term infants similarly immunized. No significant difference was demonstrated.

A group of premature infants was immunized about the time that was estimated to be their normal birth date and the antibody response compared to that of term infants at birth. The performance of the premature infants was superior to that of the term infants.

The significance of these findings is discussed.

Submitted on December 16, 1952




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