Published online May 21, 2007
PEDIATRICS Vol. 119 No. 6 June 2007, pp. e1400-e1403 (doi:10.1542/peds.2006-2605)
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EXPERIENCE & REASON

Acute Myopericarditis After Multiple Vaccinations in an Adolescent: Case Report and Review of the Literature

Maria T. Thanjan, MDa, Prema Ramaswamy, MDb, Wyman W. Lai, MD, MPHa and Irene D. Lytrivi, MDa,b

a Department of Pediatric Cardiology, Mount Sinai Medical Center, New York, New York
b Division of Pediatric Cardiology, Maimonides Medical Center, New York, New York

ABSTRACT

We report a case of postvaccination acute myopericarditis in an adolescent. The patient presented with acute chest pain, diffuse ST-segment elevation, and elevated cardiac enzyme levels. Cardiac MRI was consistent with acute myocarditis. He recovered within a few days with nonsteroidal antiinflammatory treatment and remains clinically stable, with improvement of MRI findings at the 10-week follow-up. Postvaccination cases of myopericarditis reported in the pediatric literature are also reviewed.

Key Words: immunization • myopericarditis • adolescence

Abbreviations: ECG, electrocardiogram • DTaP, diphtheria-tetanus-acellular pertussis • Ig, immunoglobulin

Accepted Nov 28, 2006.