Published online April 2, 2007
PEDIATRICS Vol. 119 No. 4 April 2007, pp. 838-845 (doi:10.1542/peds.2007-0273)
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POLICY STATEMENT

Increasing Antiretroviral Drug Access for Children With HIV Infection

Committee on Pediatric AIDS, Section on International Child Health

Although there have been great gains in the prevention of pediatric HIV infection and provision of antiretroviral therapy for children with HIV infection in resource-rich countries, many barriers remain to scaling up HIV prevention and treatment for children in resource-limited areas of the world. Appropriate testing technologies need to be made more widely available to identify HIV infection in infants. Training of practitioners in the skills required to care for children with HIV infection is required to increase the number of children receiving antiretroviral therapy. Lack of availability of appropriate antiretroviral drug formulations that are easily usable and inexpensive is a major impediment to optimal care for children with HIV. The time and energy spent trying to develop liquid antiretroviral formulations might be better used in the manufacture of smaller pill sizes or crushable tablets, which are easier to dispense, transport, store, and administer to children.

Key Words: HIV • children • antiretroviral therapy • drug formulations

Abbreviations: ARV—antiretroviral • ART—antiretroviral therapy • PEPFAR—President's Emergency Plan for AIDS Relief • WHO—World Health Organization • FDA—Food and Drug Administration • FDC—fixed-dose combination


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S. Cash
Breaking down barriers: At least 2.3 million children were living with perinatally acquired HIV infection at the end of 2005, most of them in sub-Saharan Africa. A new AAP policy statement, endorsed by organizations worldwide, offers solutions to providing antiretroviral access to children globally.
AAP News, April 1, 2007; 28(4): 15 - 15.
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