Published online January 2, 2007
PEDIATRICS Vol. 119 No. 1 January 2007, pp. 171-182 (doi:10.1542/10.1542/peds.2006-3134)
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POLICY STATEMENT

Prevention of Rotavirus Disease: Guidelines for Use of Rotavirus Vaccine

Committee on Infectious Diseases

On February 3, 2006, a bovine-based pentavalent rotavirus vaccine (RotaTeq, Merck & Co Inc, Whitehouse Station, NJ) was licensed by the US Food and Drug Administration for use in infants in the United States. The American Academy of Pediatrics recommends routine immunization of infants with 3 doses of pentavalent rotavirus vaccine administered orally at 2, 4, and 6 months of age. The first dose should be administered between 6 and 12 weeks of age; immunization should not be initiated for infants older than 12 weeks of age. Subsequent doses should be administered at 4- to 10-week intervals, and all 3 doses of vaccine should be administered by 32 weeks of age. Pentavalent rotavirus vaccine can be coadministered with other childhood vaccines. Pentavalent rotavirus vaccine is contraindicated for infants with a serious allergic reaction to any vaccine component or to a previous dose of vaccine.

Key Words: rotavirus vaccine • rotavirus gastroenteritis

Abbreviations: AAP—American Academy of Pediatrics • CDC—Centers for Disease Control and Prevention • EIA—enzyme immunoassay • Hib—Haemophilus influenzae type b • IPV—inactivated poliovirus • DTaP—diphtheria-tetanus-acellular pertussis • RRV-TV—rhesus-human rotavirus reassortant-tetravalent • SIDS—sudden infant death syndrome • VAERS—Vaccine Adverse Event Reporting System • VSD—Vaccine Safety Datalink


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The following policy statement is a revision:

Prevention of Rotavirus Disease: Updated Guidelines for Use of Rotavirus Vaccine

Pediatrics 123: 1412-1420. [Full Text]

The following policy statement has been revised:

Prevention of Rotavirus Disease: Guidelines for Use of Rotavirus Vaccine

Pediatrics 102: 1483-1491. [Full Text]



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