Published online April 3, 2006
PEDIATRICS Vol. 117 No. 4 April 2006, pp. 1372-1381 (doi:10.1542/peds.2005-0826)
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (8)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Munson, S.
Right arrow Articles by Ernst, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Munson, S.
Right arrow Articles by Ernst, M.
Related Collections
Right arrow Neurology & Psychiatry
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

REVIEW ARTICLE

The Role of Functional Neuroimaging in Pediatric Brain Injury

Suzanne Munson, BA, Elizabeth Schroth, BA and Monique Ernst, MD, PhD

Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland

The aim of this article is to review empirical studies published in the last 10 years that used various functional neuroimaging techniques to assess pediatric patients with brain injury. Overall, these studies have demonstrated the ability of functional neuroimaging to offer unique information concerning the diagnosis, clinical outcome, and recovery mechanisms after pediatric brain injury. Future research using functional neuroimaging is recommended to better understand the functional reorganization and neurodevelopmental consequences resulting from brain injury. Such research might allow clinicians to design tailored early-intervention and rehabilitation programs to maximize the recovery process for pediatric patients. Limitations and advantages associated with the use of functional neuroimaging in pediatric populations are discussed.

Key Words: brain development • functional neuroimaging • brain injury • plasticity • vulnerability

Abbreviations: GCS—Glasgow Coma Scale • PCPCS—Pediatric Cerebral Performance Category Scale • CT—computed tomography • DTI—diffusion tensor imaging • EEG—electroencephalography • fMRI—functional MRI • 1H-MRS—proton magnetic resonance spectroscopy • PET—positron emission tomography • SPECT—single-photon emission computed tomography • BOLD—blood oxygen level–dependent • NAA—N-acetyl-aspartate • Cre—creatine/phosphocreatine • Cho—cytosolic choline compound • 99Tcm-HMPAO—technetium-99m-exametazime • TE—time to echo

Accepted Sep 23, 2005.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 ptjournalHome page
L. A Boyd, E. D Vidoni, and J. J Daly
Answering the Call: The Influence of Neuroimaging and Electrophysiological Evidence on Rehabilitation
Physical Therapy, June 1, 2007; 87(6): 684 - 703.
[Abstract] [Full Text] [PDF]