Published online November 1, 2005
PEDIATRICS Vol. 116 No. 5 November 2005, pp. e732-e734 (doi:10.1542/peds.2005-0715)
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ELECTRONIC ARTICLE

Effectiveness of Iron Supplementation in a Young Child With Attention-Deficit/Hyperactivity Disorder

Eric Konofal, MD, PhD*,{ddagger}, Samuele Cortese, MD*,§, Michel Lecendreux, MD*, Isabelle Arnulf, MD, PhD{ddagger} and Marie Christine Mouren, MD*

* Service de Psychopathologie de l’Enfant et de l’Adolescent, Hôpital Robert Debré, Paris, France
{ddagger} Fédération des Pathologies du Sommeil, Hôpital Pitié Salpetrière, Paris, France
§ Servizio di Neuropsichiatria Infantile, Dipartimento Materno Infantile e di Biologia-Genetica, Università degli Studi di Verona, Verona, Italy

A 3-year-old child was referred to consultation for hyperactivity, attention deficit, impulsivity, and sleep problems. He met Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for attention-deficit/hyperactivity disorder. At baseline, the Conners’ Parent Rating Scale and the Conners’ Teacher Rating Scale raw total scores were 30 and 32, respectively. The child had low a serum ferritin level (13 ng/mL). After 8 months of treatment with Tardyferon (ferrous sulfate, 80 mg/day), his serum ferritin increased to 102 ng/mL. Both parents and teachers reported considerable behavioral improvement. The Conners’ Parent and Teacher Rating Scale raw total scores decreased to 19 and 13, respectively. This is the first report of the effectiveness of iron supplementation in a young child with attention-deficit/hyperactivity disorder.


Key Words: ADHD • iron deficiency

Abbreviations: ADHD, attention-deficit/hyperactivity disorder • DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition • RLS, restless legs syndrome


Accepted May 31, 2005.


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[Abstract] [PDF]