Published online September 30, 2005
PEDIATRICS Vol. 116 No. 4 October 2005, pp. 933-938 (doi:10.1542/peds.2004-2806)
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow An erratum has been published
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (23)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Berg, A. L.
Right arrow Articles by Diamond, B. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Berg, A. L.
Right arrow Articles by Diamond, B. E.
Related Collections
Right arrow Dentistry & Otolaryngology
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Newborn Hearing Screening in the NICU: Profile of Failed Auditory Brainstem Response/Passed Otoacoustic Emission

Abbey L. Berg, PhD*,{ddagger}, Jaclyn B. Spitzer, PhD{ddagger}, Helen M. Towers, MD§, Christine Bartosiewicz, BA{ddagger} and Beverly E. Diamond, DSW||

* Department of Communication Studies/Communication Sciences and Disorders, Dyson College of Arts and Sciences, Pace University, New York, New York
{ddagger} Audiology and Speech Pathology Division, Department of Otolaryngology/Head and Neck Surgery
§ Department of Pediatrics
|| Irving Center for Clinical Research, Columbia University Medical Center, New York, New York

Objective. Incidence of a specific pattern of auditory responses, absent auditory brainstem responses (ABRs) and present otoacoustic emissions (OAEs), in newborn hearing screening in a regional perinatal center neonatal intensive care unit (NICU) is described. This profile, labeled auditory neuropathy or auditory dyssynchrony (AN/AD), is a dysfunction in neural/brainstem transmission that occurs in individuals whose outer hairs cells are functioning normally. Although the AN/AD profile has been associated with various risk factors, incidence and prediction are unknown.

Method. Analysis of electrophysiologic measures and medical record reviews of the first 22 months of the universal newborn hearing–screening program was conducted. Association of the AN/AD profile was evaluated with the following factors: gender, gestational age, ototoxic drug regimen, low birth weight, hyperbilirubinemia, hydrocephalus, low Apgar score, anoxia, respiratory distress syndrome, pulmonary hypertension, intraventricular hemorrhage, multiple birth, seizure activity, and family history.

Results. One hundred fifteen (24.1%) of the 477 infants failed the ABR in 1 or both ears and passed OAEs bilaterally. Comparisons of infants fitting the AN/AD profile with those not fitting the AN/AD profile were negative with 3 exceptions: those with hyperbilirubinemia and those who were administered vancomycin or furosemide. A logistic-regression analysis model failed to predict which infants would be at risk for the AN/AD profile either unilaterally or bilaterally.

Conclusions. Screening of NICU infants should be conducted with ABR first, followed by OAE after failure on ABR. Because the incidence of the AN/AD profile was found to be 24% in this at-risk population, additional study is warranted.

Key Words: auditory neuropathy/dyssynchrony • newborn hearing screening • infants • hyperbilirubinemia • ototoxicity • auditory brainstem response • otoacoustic emissions • neonatal intensive care • prematurity

Abbreviations: ABR, auditory brainstem response • OAE, otoacoustic emission • CM, cochlear microphonics • AN, auditory neuropathy • AD, auditory dyssynchrony • GA, gestational age • CUMC, Columbia University Medical Center • DPOAE, distortion-product otoacoustic emission

Accepted May 2, 2005.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 PediatricsHome page
F. Declau, A. Boudewyns, J. Van den Ende, A. Peeters, and P. van den Heyning
Etiologic and Audiologic Evaluations After Universal Neonatal Hearing Screening: Analysis of 170 Referred Neonates
Pediatrics, June 1, 2008; 121(6): 1119 - 1126.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
C. E. Ahlfors and A. E. Parker
Unbound Bilirubin Concentration is Associated With Abnormal Automated Auditory Brainstem Response for Jaundiced Newborns
Pediatrics, May 1, 2008; 121(5): 976 - 978.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
Joint Committee on Infant Hearing
Year 2007 Position Statement: Principles and Guidelines for Early Hearing Detection and Intervention Programs
Pediatrics, October 1, 2007; 120(4): 898 - 921.
[Full Text] [PDF]