Published online July 15, 2005
PEDIATRICS Vol. 116 No. 2 August 2005, pp. e322-e325 (doi:10.1542/peds.2005-0026)
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ELECTRONIC ARTICLE

Histiocytic Sarcoma in a 3-Year-Old Male: A Case Report

Samuel Buonocore, MD*, Alfredo L. Valente, MD{ddagger}, Daniel Nightingale, MD{ddagger}, Jeffrey Bogart, MD§ and Abdul-Kader Souid, MD, PhD*

* Departments of Pediatrics
{ddagger} Pathology
§ Radiation Oncology, State University of New York, Upstate Medical University, Syracuse, New York

We describe a pediatric patient with histiocytic sarcoma involving the T6 and L4 vertebral bodies and the lungs. His tumor progressed during chemotherapy designed for Langerhans' cell histiocytosis and sarcoma. High-dose radiation, on the other hand, was effective.

Key Words: sarcoma • histiocytes • Langerhans' cell histiocytosis • histiocytic sarcoma

Abbreviations: LCH, Langerhans' cell histiocytosis • CT, computed tomography • 2CdA, 2-chlorodeoxyadenosine

Accepted Feb 28, 2005.