PEDIATRICS Vol. 114 No. 3 September 2004, pp. 782-785 (doi:10.1542/10.1542/peds.2004-0390)
Intussusception in Early Childhood: A Cohort Study of 1.7 Million Children





* Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
Departments of Epidemiology Research
|| Epidemiology, Statens Serum Institut
Department of Internal Medicine, Amager University Hospital, Copenhagen, Denmark
Objective. To describe incidence and temporal trends of intussusceptions in Danish children during 1980 to 2001.
Methods. A population-based cohort study was conducted of 1.67 million children who were younger than 5 years during 1980 to 2001 and were followed up for 6.66 million person-years. The Danish National Patient Registry was used to identify cases of intussusception in the cohort. Age-specific incidence rates were main outcome measure.
Results. A total of 1814 cases of intussusception among children who were younger than 5 years were reported from 1980 to 2001. The incidence rate remained fairly constant during 1980 to 1990 but decreased by 55% (95% confidence interval: 43%65%) from 1990 to 2001. The reduction was most pronounced among children aged 3 to 5 months.
Conclusions. The incidence of intussusception among Danish children declined significantly during the 1990s, particularly among infants 3 to 5 months of age.
Key Words: children incidence intussusception population-based studies
Abbreviations: NPR, National Patient Registry ICD, International Classification of Diseases CI, confidence interval
Accepted Apr 28, 2004.
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