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PEDIATRICS Vol. 114 No. 2 August 2004, pp. e270-e272

ELECTRONIC ARTICLE

All That Is Vesicular Is Not Herpes: Incontinentia Pigmenti Masquerading as Herpes Simplex Virus in a Newborn

Morayo Faloyin*, Jacob Levitt, MD{ddagger}, Eric Bercowitz, MD{ddagger}, Daniel Carrasco, MD{ddagger} and Jianyou Tan, MD§

* College of Medicine, University of Illinois, Rockford, Illinois
{ddagger} Department of Dermatology, Mount Sinai Medical Center, New York, New York
§ Department of Dermpathology, Mount Sinai Medical Center, New York, New York

Incontinentia pigmenti is a multisystem genodermatosis characterized by cutaneous, neurologic, ophthalmologic, and dental abnormalities. The skin lesions associated with the disease progress through 4 stages, the first being erythematous vesicles linearly distributed along the lines of Blaschko. We report a case of an infant who had incontinentia pigmenti and presented with 2 crops of vesicles and was initially thought to have herpes simplex virus.

Key Words: incontinentia pigmenti • herpes simplex virus • Block-Sulzberger syndrome

Abbreviations: IP, incontinentia pigmenti • HSV, herpes simplex virus • CNS, central nervous system • WBCs, white blood cells

Received for publication Jan 12, 2004; Accepted Mar 26, 2004.