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PEDIATRICS Vol. 113 No. 6 June 2004, pp. 1741-1746

Pediatric Patient Safety in Hospitals: A National Picture in 2000

Marlene R. Miller, MD* and Chunliu Zhan, MD, PhD{ddagger}

* Department of Pediatrics, Johns Hopkins University, Baltimore, Maryland
{ddagger} Center for Quality Improvement and Patient Safety, Agency for Healthcare Research and Quality, Rockville, Maryland

Objective. To describe potential patient safety events for hospitalized children, examine associated factors, and explore impacts of safety events.

Methods. The newly released Patient Safety Indicators (PSIs), developed by researchers at the Agency for Healthcare Research and Quality to identify potential in-hospital patient safety problems using administrative data, were applied to hospital discharge data. All 5.7 million discharge records for children younger than 19 years from 27 states in the 2000 Healthcare Cost and Utilization Project were analyzed for PSI events. Prevalence of PSI events and associations with patient-level and hospital-level characteristics were examined. Multivariate regression adjusting for patient severity of illness was used to estimate impacts of safety events in terms of excess length of stay, charges, and in-hospital mortality.

Results. The prevalence of pediatric patient safety events is significant. PSI events occurred more frequently in the very young and those on Medicaid insurance, some of the most vulnerable hospitalized children. Regression analysis found that almost all PSIs are associated with significant and substantial increases in length of stay, charges, and in-hospital death. Using the estimates derived here and the actual number of cases identified in the 2000 data, we estimate that patient safety events incurred >$1 billion in excess charges for children alone in 2000.

Conclusions. Patient safety problems for hospitalized children occur frequently and with substantial impacts to our health care industry. Unmeasurable by this study are the additional "costs" and "burdens" of safety events that our patients are forced to handle. Additional work to describe and quantify better these outcomes in addition to ones measured here can help solidify the "business case" for patient safety efforts.


Key Words: safety • quality of health care • medical error • infant • child • adolescent • inpatients • hospitals

Abbreviations: AHRQ, Agency for Healthcare Research and Quality • PSI, Patient Safety Indicator • LOS, length of stay • DRG, diagnosis-related group • OR, odds ratio • CI, confidence interval


Received for publication Sep 9, 2003; Accepted Jan 26, 2004.


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