This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via ISI Web of Science (9)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Armengol, C. E.
Right arrow Articles by Hendley, J. O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Armengol, C. E.
Right arrow Articles by Hendley, J. O.
Related Collections
Right arrow Infectious Disease & Immunity
PEDIATRICS Vol. 113 No. 4 April 2004, pp. 924-926

EXPERIENCE AND REASON

Sensitivity of a Rapid Antigen Detection Test for Group A Streptococci in a Private Pediatric Office Setting: Answering the Red Book’s Request for Validation

Carlos E. Armengol, MD*,{ddagger}, Theresa A. Schlager, MD{ddagger} and J. Owen Hendley, MD{ddagger}

* Pediatric Associates of Charlottesville
{ddagger} Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia

In the office laboratory of our private practice, the sensitivity of a single rapid antigen detection (RAD) test for group A streptococci (compared with backup throat culture) was examined over 3 winter periods. When cultures were held only 24 hours, the sensitivity was 92%; in the second period, when cultures were held to 48 hours, the sensitivity declined significantly to 86%; when the cultures were read without knowledge of the RAD test result, the sensitivity was 85%. As the Red Book Committee has suggested, physician office laboratories should validate the sensitivity of their RAD test against culture onto blood agar before abandoning the backup throat culture.

Key Words: group A ß-hemolytic streptococci • rapid antigen detection test

Abbreviations: GABHS, group A ß-hemolytic streptococci/streptococcal • RAD, rapid antigen detection • IDSA, Infectious Disease Society of America • OIA, optical immunoassay

Received for publication Feb 24, 2003; Accepted Aug 18, 2003.




This article has been cited by other articles:


Home page
 J. Clin. Microbiol.Home page
J. W. Fox, D. M. Cohen, M. J. Marcon, W. H. Cotton, and B. K. Bonsu
Performance of Rapid Streptococcal Antigen Testing Varies by Personnel
J. Clin. Microbiol., November 1, 2006; 44(11): 3918 - 3922.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
S. Y. Park, M. A. Gerber, R. R. Tanz, J. M. Hickner, J. M. Galliher, I. Chuang, and R. E. Besser
Clinicians' management of children and adolescents with acute pharyngitis.
Pediatrics, June 1, 2006; 117(6): 1871 - 1878.
[Abstract] [Full Text] [PDF]

Home page
 Emerg. Med. J.Home page
J Van Limbergen, P Kalima, S Taheri, and T F Beattie
Streptococcus A in paediatric accident and emergency: are rapid streptococcal tests and clinical examination of any help?
Emerg. Med. J., January 1, 2006; 23(1): 32 - 34.
[Abstract] [Full Text] [PDF]