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Can We Predict Which Children With Clinically Suspected Pneumonia Will Have the Presence of Focal Infiltrates on Chest Radiographs?
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* Department of Pediatrics, Childrens Hospital of Western Ontario, London, Ontario, Canada
Departments of Epidemiology
Biostatistics, Montreal Childrens Hospital, McGill University, Montreal, Quebec, Canada
|| Department of Pediatrics, Ste-Justine Hospital, University of Montreal, Montreal, Quebec, Canada
¶ Departments of Pediatrics
# Radiology, Montreal Childrens Hospital, McGill University, Montreal, Quebec, Canada
Objective. To determine predictive factors for the presence of focal infiltrates in children with clinically suspected pneumonia in a pediatric emergency department.
Methods. Children (116 years) with clinically suspected pneumonia were studied prospectively. The presenting features were compared between the children with and without focal infiltrates using
2 analysis, t test, and odds ratio with 95% confidence intervals. A multivariate prediction rule was developed using logistic regression.
Results. A total of 570 were studied. Risk factors (odds ratio; 95% confidence interval) for the presence of focal infiltrates included history of fever (3.1; 1.75.3), decreased breath sounds (1.4; 1.02.0), crackles (2.0; 1.42.9), retractions (2.8; 1.07.6), grunting (7.3; 1.148.1), fever (1.5; 1.21.9), tachypnea (1.8; 1.32.5), and tachycardia (1.3; 1.01.6). We then used logistic regression to develop a candidate prediction rule for the variables of fever, decreased breath sounds, crackles, and tachypnea, which had an area under the receiver operating curve of 0.668. This rule had excellent sensitivity (93.1%98%) yet poor specificity (5.7%19.4%).
Conclusions. Multiple predictive factors for children with suspected pneumonia have been identified. Patients with focal infiltrates were more likely in our study to have a history of fever, tachypnea, increased heart rate, retractions, grunting, crackles, or decreased breath sounds. A multivariate prediction rule shows promise for the accurate prediction of pneumonia in children. However, the prospective evaluation of this multivariate prediction rule in a clinical setting is still required.
Key Words: pneumonia chest radiographs children predictive factors
Abbreviations: ED, emergency department OR, odds ratio CI, confidence interval
Received for publication Feb 24, 2003; Accepted Oct 21, 2003.
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