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PEDIATRICS Vol. 112 No. 6 December 2003, pp. e491-e494

EXPERIENCE AND REASON

Henoch-Schonlein Purpura Following a Meningococcal Vaccine

Emily M. Lambert, MSV*, Anne Liebling, MD*,{ddagger},§, Earl Glusac, MD*,||,¶ and Richard J. Antaya, MD*,{ddagger},¶

{ddagger} Departments of Pediatrics
§ Internal Medicine
|| Pathology
Dermatology
* Yale University School of Medicine, New Haven Connecticut

We report a 17-year-old girl who developed Henoch-Schonlein purpura 10 days after receiving a meningococcal vaccine (Menomune). To our knowledge, this is the first case report of Henoch-Schonlein purpura temporally associated with the tetravalent serogroups A, C, W-135, and Y meningococcal vaccine administered in the United States.

Key Words: Henoch-Schonlein purpura • meningococcus • Meningitec • vaccine • leukocytoclastic vasculitis • vasculitis

Abbreviations: HSP, Henoch-Schonlein purpura • LCV, leukocytoclastic vasculitis • IgA, immunoglobulin A

Received for publication Oct 14, 2002; Accepted Aug 21, 2003.