This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kirton, A.
Right arrow Articles by Hill, M. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kirton, A.
Right arrow Articles by Hill, M. D.
Related Collections
Right arrow Heart & Blood Vessels
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?
PEDIATRICS Vol. 112 No. 3 September 2003, pp. e248-e251

ELECTRONIC ARTICLE

Successful Endovascular Therapy for Acute Basilar Thrombosis in an Adolescent

Adam Kirton, MD, John H. Wong, MD, MSc, FRCSC, Jean Mah, MD, FRCPC, B. Catherine Ross, MD, FRCPC, James Kennedy, MB, MSc, MRCP, Katherine Bell, MB, FRCR and Michael D. Hill, MD, FRCPC

From the Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada

Pediatric stroke is an underrecognized, potentially treatable cause of childhood neurologic disease. Acute basilar artery thrombosis is a devastating disease rarely encountered in children. Acute interventions with both chemical and mechanical thrombolysis techniques can improve outcomes in adults with arterial thrombosis of the posterior cerebral circulation. We report a case of intervention with both intra-arterial alteplase (tissue plasminogen activator) and cerebral balloon angioplasty to treat a prolonged basilar artery occlusion secondary to idiopathic thrombosis in an adolescent. Despite the patient being clinically locked-in and intervention being delayed at least 20 hours from symptom onset, he obtained complete neurologic recovery. Issues of pediatric stroke, late therapeutic intervention, chemical thrombolysis, and cerebral angioplasty are discussed. This case highlights the underrecognition and subsequent delay in diagnosis of pediatric stroke and how acute intervention may cure otherwise catastrophic strokes in children.

Key Words: stroke • child • basilar artery • thrombosis • balloon angioplasty • alteplase

Abbreviations: CT, computed tomography (scan) • MRI, magnetic resonance imaging

Received for publication Jan 2, 2003; Accepted May 1, 2003.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 StrokeHome page
M. Arnold, M. Steinlin, A. Baumann, K. Nedeltchev, L. Remonda, S. J. Moser, M.-L. Mono, G. Schroth, H. P. Mattle, and R. W. Baumgartner
Thrombolysis in Childhood Stroke: Report of 2 Cases and Review of the Literature
Stroke, March 1, 2009; 40(3): 801 - 807.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
E. S. Roach, M. R. Golomb, R. Adams, J. Biller, S. Daniels, G. deVeber, D. Ferriero, B. V. Jones, F. J. Kirkham, R. M. Scott, et al.
Management of Stroke in Infants and Children: A Scientific Statement From a Special Writing Group of the American Heart Association Stroke Council and the Council on Cardiovascular Disease in the Young
Stroke, September 1, 2008; 39(9): 2644 - 2691.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
N. Janjua, A. Nasar, J. K. Lynch, and A. I. Qureshi
Thrombolysis for Ischemic Stroke in Children: Data From the Nationwide Inpatient Sample
Stroke, June 1, 2007; 38(6): 1850 - 1854.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
R. Belvis
Thrombolysis for Acute Stroke in Pediatrics
Stroke, June 1, 2007; 38(6): 1722 - 1723.
[Full Text] [PDF]

Home page
 CirculationHome page
H. P. Adams Jr, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, et al.
Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists.
Circulation, May 22, 2007; 115(20): e478 - e534.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
H. P. Adams Jr, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, et al.
Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/ American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists
Stroke, May 1, 2007; 38(5): 1655 - 1711.
[Abstract] [Full Text] [PDF]

Home page
 J Child NeurolHome page
S. L. Benedict, O. K. Ni, P. Schloesser, K. S. White, and J. F. Bale Jr
Intra-arterial Thrombolysis in a 2-Year-Old with Cardioembolic Stroke
J Child Neurol, February 1, 2007; 22(2): 225 - 227.
[Abstract] [PDF]