This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via ISI Web of Science (40)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Holman, R. C.
Right arrow Articles by Schonberger, L. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Holman, R. C.
Right arrow Articles by Schonberger, L. B.
Related Collections
Right arrow Infectious Disease & Immunity
Right arrowRelated AAP Red Book topics:
Kawasaki Disease (Mucocutaneous...
PEDIATRICS Vol. 112 No. 3 September 2003, pp. 495-501

Kawasaki Syndrome Hospitalizations in the United States, 1997 and 2000

Robert C. Holman, MS*, Aaron T. Curns, MPH*, Ermias D. Belay, MD*, Claudia A. Steiner, MD, MPH{ddagger} and Lawrence B. Schonberger, MD, MPH*

* Office of the Director, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, Georgia
{ddagger} Healthcare Cost and Utilization Project, Center for Organization and Delivery Studies, Agency for Healthcare Research and Quality, US Department of Health and Human Service, Rockville, Maryland

Objective. To estimate the incidence and describe the epidemiologic characteristics of Kawasaki syndrome (KS) among children in the United States.

Methods. Hospital discharge records with a KS diagnosis among patients <18 years of age were obtained from the 1997 and 2000 Kids’ Inpatient Database and weighted to estimate the number and rate of KS-associated hospitalizations for the United States.

Results. In 2000, ~4248 hospitalizations associated with KS occurred in the United States, and the median age of patients at admission was 2 years. Children <5 years of age accounted for 3277 of these KS hospitalizations (77%) and had a KS hospitalization rate of 17.1 per 100 000 children. This rate was similar to the 1997 rate of 17.6 per 100 000 children. The KS hospitalization rate was significantly higher for infants <1 year of age than for children 1 to 4 years of age (19.8 and 16.4 per 100 000 children, respectively). The rate of KS hospitalizations among children aged <5 years was highest among Asian and Pacific Islander children and was followed by the rate for black children (39.0 and 19.7 per 100 000 children, respectively). No deaths associated with KS were reported among hospitalized children. The median charge for a KS hospitalization was $7779 (mean $10 725) and the total annual charges for KS hospitalizations in 2000 were approximately $35 million among children <5 years of age.

Conclusions. Among children <5 years of age, the annual KS-associated hospitalization rates were similar for 1997 and 2000. The epidemiologic characteristics and hospitalization rates for KS at a national level were consistent with those reported from earlier studies, suggesting that the incidence for KS has not markedly changed in the United States during the past decade.

Key Words: Kawasaki syndrome • Kawasaki disease • hospitalizations • epidemiology • children • infants • United States

Abbreviations: KS, Kawasaki syndrome • KID, Kids’ Inpatient Database • HCUP, Healthcare Cost and Utilization Project • ICD-9-CM, International Classification of Diseases, Ninth Revision, Clinical Modification • SE, standard error • CI, confidence interval • CDC, Centers for Disease Control and Prevention • NIS, Nationwide Inpatient Sample

Received for publication Jan 10, 2003; Accepted Mar 11, 2003.




This article has been cited by other articles:


Home page
 CirculationHome page
W. Rosamond, K. Flegal, G. Friday, K. Furie, A. Go, K. Greenlund, N. Haase, M. Ho, V. Howard, B. Kissela, et al.
Heart Disease and Stroke Statistics--2007 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Circulation, February 6, 2007; 115(5): e69 - e171.
[Full Text] [PDF]

Home page
 CirculationHome page
R.-E. W. Kavey, V. Allada, S. R. Daniels, L. L. Hayman, B. W. McCrindle, J. W. Newburger, R. S. Parekh, and J. Steinberger
Cardiovascular Risk Reduction in High-Risk Pediatric Patients: A Scientific Statement From the American Heart Association Expert Panel on Population and Prevention Science; the Councils on Cardiovascular Disease in the Young, Epidemiology and Prevention, Nutrition, Physical Activity and Metabolism, High Blood Pressure Research, Cardiovascular Nursing, and the Kidney in Heart Disease; and the Interdisciplinary Working Group on Quality of Care and Outcomes Research: Endorsed by the American Academy of Pediatrics
Circulation, December 12, 2006; 114(24): 2710 - 2738.
[Abstract] [Full Text] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
J. M. Robbins, T. M. Bird, J. M. Tilford, J. A. Reading, M. A. Cleves, M. E. Aitken, C. M. Druschel, and C. A. Hobbs
Reduction in Newborns With Discharge Coding of In Utero Alcohol Effects in the United States, 1993 to 2002
Arch Pediatr Adolesc Med, December 1, 2006; 160(12): 1224 - 1231.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
J. M. Robbins, J. M. Tilford, T.M. Bird, M. A. Cleves, J. A. Reading, and C. A. Hobbs
Hospitalizations of Newborns With Folate-Sensitive Birth Defects Before and After Fortification of Foods With Folic Acid
Pediatrics, September 1, 2006; 118(3): 906 - 915.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
F. O. Odetola, J. M. Tilford, and M. M. Davis
Variation in the use of intracranial-pressure monitoring and mortality in critically ill children with meningitis in the United States.
Pediatrics, June 1, 2006; 117(6): 1893 - 1900.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
T. Thom, N. Haase, W. Rosamond, V. J. Howard, J. Rumsfeld, T. Manolio, Z.-J. Zheng, K. Flegal, C. O'Donnell, S. Kittner, et al.
Heart Disease and Stroke Statistics--2006 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Circulation, February 14, 2006; 113(6): e85 - e151.
[Full Text] [PDF]

Home page
 CLIN PEDIATRHome page
W. M. Abuhammour, R. A. Hasan, A. Eljamal, and B. Asmar
Kawasaki Disease Hospitalizations in a Predominantly African-American Population
Clinical Pediatrics, October 1, 2005; 44(8): 721 - 725.
[Abstract] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
M. Dergun, A. Kao, S. B. Hauger, J. W. Newburger, and J. C. Burns
Familial Occurrence of Kawasaki Syndrome in North America
Arch Pediatr Adolesc Med, September 1, 2005; 159(9): 876 - 881.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
J. B. Killingsworth, J. M. Tilford, J. G. Parker, J. J. Graham, R. M. Dick, and M. E. Aitken
National Hospitalization Impact of Pediatric All-Terrain Vehicle Injuries
Pediatrics, March 1, 2005; 115(3): e316 - e321.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
J. W. Newburger, M. Takahashi, M. A. Gerber, M. H. Gewitz, L. Y. Tani, J. C. Burns, S. T. Shulman, A. F. Bolger, P. Ferrieri, R. S. Baltimore, et al.
Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association
Pediatrics, December 1, 2004; 114(6): 1708 - 1733.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
L.-Y. Chang, I-S. Chang, C.-Y. Lu, B.-L. Chiang, C.-Y. Lee, P.-J. Chen, J.-T. Wang, H.-N. Ho, D.-S. Chen, L.-M. Huang, et al.
Epidemiologic Features of Kawasaki Disease in Taiwan, 1996-2002
Pediatrics, December 1, 2004; 114(6): e678 - e682.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
J. W. Newburger, M. Takahashi, M. A. Gerber, M. H. Gewitz, L. Y. Tani, J. C. Burns, S. T. Shulman, A. F. Bolger, P. Ferrieri, R. S. Baltimore, et al.
Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association
Circulation, October 26, 2004; 110(17): 2747 - 2771.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
H. C. Meissner and D. Y. M. Leung
Kawasaki Syndrome: Where Are the Answers?
Pediatrics, September 1, 2003; 112(3): 672 - 676.
[Full Text] [PDF]