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PEDIATRICS Vol. 112 No. 2 August 2003, pp. e162-e167


EXPERIENCE AND REASON

Cerebral Embolism From Atrial Myxoma in Pediatric Patients

Majeed Al-Mateen, MD*,{ddagger}, Margaret Hood, MD*, Don Trippel, MD*, Samuel J. Insalaco, MD*,§, Randolph K. Otto, MD*, Kari J. Vitikainen, MD*

* Mary Bridge Children’s Hospital and Health Center and Tacoma General Hospital, Tacoma, Washington
{ddagger} Department of Neurology, University of Washington School of Medicine, Seattle, Washington
§ Department of Pathology, University of Washington School of Medicine, Seattle, Washington

We describe 2 children with cerebrovascular events caused by emboli from left atrial myxomas and review 7 other pediatric cases from the literature. Transient cutaneous eruptions involving the extremities preceded the cerebrovascular events and were most likely attributable to fragmentation of the atrial tumor with peripheral embolization. Our first case demonstrates the more common presentation with acute hemiplegia caused by cerebral infarction and the second case a transient ischemic attack manifested by more subtle features as a result of involvement of the vertebrobasilar circulation. Neither child had a history or other signs of cardiac disease. Atrial myxoma should be considered in the differential diagnosis when children present with neurologic symptoms or with signs of embolization, because surgical removal of the tumor is critical and may be curative.


Key Words: cardiac myxoma • acute hemiplegia (in children) • stroke • evanescent rash • retinal artery occlusion

Abbreviations: MRI, magnetic resonance imaging


Received for publication Jan 6, 2003; Accepted Apr 23, 2003.


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