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PEDIATRICS Vol. 112 No. 1 July 2003, pp. 183-185

EXPERIENCE AND REASON

Pemphigus Vulgaris: The Eyes Have It

Saba Merchant, MD and Michael Weinstein, MD

Department of Paediatrics
Hospital for Sick Children
University of Toronto
Toronto, Canada M5G 1X8
Division of Paediatric Medicine
Hospital for Sick Children
University of Toronto
Toronto, Canada M5G 1X8

Pemphigus vulgaris is a potentially fatal autoimmune blistering disease that is rare in childhood. We report 2 recent cases seen contemporaneously in adolescents who presented with chronic oral mucosal lesions and conjunctivitis. The previously unemphasized ocular manifestations are described and the importance of a biopsy in establishing the diagnosis in instances of unexplained chronic mucositis is stressed.

Key Words: pemphigus • conjunctivitis

Abbreviations: PV, pemphigus vulgaris • IgG, immunoglobulin G • IV, intravenous

Received for publication Oct 30, 2002; Accepted Jan 31, 2003.


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