This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Web of Science (40)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Winter, S.
Right arrow Articles by Yeargin-Allsopp, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Winter, S.
Right arrow Articles by Yeargin-Allsopp, M.
Related Collections
Right arrow Premature & Newborn
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

PEDIATRICS Vol. 110 No. 6 December 2002, pp. 1220-1225

Trends in the Prevalence of Cerebral Palsy in a Population-Based Study

Sarah Winter, MD*, Andrew Autry, PhD{ddagger}, Coleen Boyle, PhD{ddagger} and Marshalyn Yeargin-Allsopp, MD{ddagger}

* Department of Pediatrics, Emory University, Atlanta, Georgia;
{ddagger} National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia

--> Objective. To determine trends in the prevalence of congenital cerebral palsy (CP) over a 16-year period for 1-year survivors using a large, population-based surveillance program.

Methods. We determined birth weight-specific trends in the prevalence of CP in live birth and 1-year survivor cohorts of children in a 5-county metropolitan Atlanta area for the periods from 1975–1977, 1981–1985, and 1986–1991. We ascertained children with CP in metropolitan Atlanta by record review as part of an ongoing developmental disability surveillance program conducted by the Centers for Disease Control and Prevention and the Georgia Department of Human Resources. A total of 110, 262, and 443 cases of congenital CP were identified for the birth years 1975–1977, 1981–1985, and 1986–1991, respectively. Data were analyzed by birth weight, race, subtypes of CP, and whether the CP existed as an isolated disability or was accompanied by another disability.

Results. There was a modest increase in the overall prevalence of congenital CP from 1.7 to 2.0 per 1000 1-year survivors during the period from 1975–1991. This trend was primarily attributable to a slight increase in CP in infants of normal birth weight—CP rates in moderately low and very low birth weight infants did not show consistent trends. There was an increase in the proportion of children who had CP and no other disabilities that was most apparent in infants of normal birth weight from 17% in 1975–1977 to 39% in 1986–1991. For children weighing <1500 g, the proportion of children with spastic diplegic CP increased over time (7% of cases in 1975–1977, 36% in 1985–1988, and 32% in 1986–1991).

Conclusions. In the only ongoing population-based study of CP in the United States, there has been a modest increase in the prevalence of CP in 1-year survivors born from 1975–1991. This increase however was seen only in infant survivors of normal birth weight. No change was seen in the trends in CP prevalence in low birth weight and very low birth weight infant based on infant survivors.

Key Words: cerebral palsy • epidemiology • trends • prevalence • developmental disability

Abbreviations: CP, cerebral palsy • CDC, Centers for Disease Control • Prevention

Received for publication Feb 21, 2002; Accepted Jul 30, 2002.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 NEJMHome page
D. J. Rouse, D. G. Hirtz, E. Thom, M. W. Varner, C. Y. Spong, B. M. Mercer, J. D. Iams, R. J. Wapner, Y. Sorokin, J. M. Alexander, et al.
A Randomized, Controlled Trial of Magnesium Sulfate for the Prevention of Cerebral Palsy
N. Engl. J. Med., August 28, 2008; 359(9): 895 - 905.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
J.-C. Fauchere, C. Dame, R. Vonthein, B. Koller, S. Arri, M. Wolf, and H. U. Bucher
An Approach to Using Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants
Pediatrics, August 1, 2008; 122(2): 375 - 382.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
J. Zeitlin, E. S. Draper, L. Kollee, D. Milligan, K. Boerch, R. Agostino, L. Gortner, P. Van Reempts, J.-L. Chabernaud, J. Gadzinowski, et al.
Differences in Rates and Short-term Outcome of Live Births Before 32 Weeks of Gestation in Europe in 2003: Results From the MOSAIC Cohort
Pediatrics, April 1, 2008; 121(4): e936 - e944.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
M. Yeargin-Allsopp, K. Van Naarden Braun, N. S. Doernberg, R. E. Benedict, R. S. Kirby, and M. S. Durkin
Prevalence of Cerebral Palsy in 8-Year-Old Children in Three Areas of the United States in 2002: A Multisite Collaboration
Pediatrics, March 1, 2008; 121(3): 547 - 554.
[Abstract] [Full Text] [PDF]

Home page
 JAMAHome page
C. M. T. Robertson, M.-J. Watt, and Y. Yasui
Changes in the Prevalence of Cerebral Palsy for Children Born Very Prematurely Within a Population-Based Program Over 30 Years
JAMA, June 27, 2007; 297(24): 2733 - 2740.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
D. Hirtz, D. J. Thurman, K. Gwinn-Hardy, M. Mohamed, A. R. Chaudhuri, and R. Zalutsky
How common are the "common" neurologic disorders?
Neurology, January 30, 2007; 68(5): 326 - 337.
[Abstract] [Full Text] [PDF]

Home page
 J Trop PediatrHome page
J. Liu, Q. Wang, J.-h. Zhao, Y.-h. Chen, and G.-l. Qin
The Combined Antenatal Corticosteroids and Vitamin K Therapy for Preventing Periventricular-Intraventricular Hemorrhage in Premature Newborns less than 35 weeks Gestation
J Trop Pediatr, October 1, 2006; 52(5): 355 - 359.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
Y. W. Wu, L. A. Croen, S. J. Shah, T. B. Newman, and D. V. Najjar
Cerebral Palsy in a Term Population: Risk Factors and Neuroimaging Findings
Pediatrics, August 1, 2006; 118(2): 690 - 697.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
T. B. Newman, P. Liljestrand, R. J. Jeremy, D. M. Ferriero, Y. W. Wu, E. S. Hudes, G. J. Escobar, and the Jaundice and Infant Feeding Study Team
Outcomes among newborns with total serum bilirubin levels of 25 mg per deciliter or more.
N. Engl. J. Med., May 4, 2006; 354(18): 1889 - 1900.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
P.-Y. Ancel, F. Livinec, B. Larroque, S. Marret, C. Arnaud, V. Pierrat, M. Dehan, S. N'Guyen, B. Escande, A. Burguet, et al.
Cerebral Palsy Among Very Preterm Children in Relation to Gestational Age and Neonatal Ultrasound Abnormalities: The EPIPAGE Cohort Study
Pediatrics, March 1, 2006; 117(3): 828 - 835.
[Abstract] [Full Text] [PDF]

Home page
 NeoReviewsHome page
N. Paneth, S. Korzeniewski, and T. Hong
The Role of the Intrauterine and Perinatal Environment in Cerebral Palsy
NeoReviews, March 1, 2005; 6(3): e133 - e140.
[Full Text] [PDF]

Home page
 PediatricsHome page
Y. W. Wu, K. H. Backstrand, S. Zhao, H. J. Fullerton, and S. C. Johnston
Declining Diagnosis of Birth Asphyxia in California: 1991-2000
Pediatrics, December 1, 2004; 114(6): 1584 - 1590.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
D. M. Ferriero
Neonatal Brain Injury
N. Engl. J. Med., November 4, 2004; 351(19): 1985 - 1995.
[Full Text] [PDF]

Home page
 JAMAHome page
Y. W. Wu, G. J. Escobar, J. K. Grether, L. A. Croen, J. D. Greene, and T. B. Newman
Chorioamnionitis and Cerebral Palsy in Term and Near-Term Infants
JAMA, November 26, 2003; 290(20): 2677 - 2684.
[Abstract] [Full Text] [PDF]

Home page
 JAMAHome page
J. E. Tyson and L. C. Gilstrap
Hope for Perinatal Prevention of Cerebral Palsy
JAMA, November 26, 2003; 290(20): 2730 - 2732.
[Full Text] [PDF]

Home page
 NEJMHome page
K. B. Nelson
Can We Prevent Cerebral Palsy?
N. Engl. J. Med., October 30, 2003; 349(18): 1765 - 1769.
[Full Text] [PDF]