This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fleisher, B. E.
Right arrow Articles by Bernstein, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fleisher, B. E.
Right arrow Articles by Bernstein, D.
Related Collections
Right arrow Heart & Blood Vessels

PEDIATRICS Vol. 109 No. 1 January 2002, pp. 1-7

Infant Heart Transplantation at Stanford: Growth and Neurodevelopmental Outcome

Barry E. Fleisher, MD*, David Baum, MD*, Ginger Brudos, PhD*, Mary Burge, LCSW, MCSW*, Elaine Carson, RNa, Janet Constantinou, MA*, Josh Duckworth, BSb, Pat Gamberg, RN{ddagger}, Pat Klein, MA*, Helen Luikart, RN{ddagger}, Joan Miller, RN{ddagger}, Brad Stach, PhD§ and Dan Bernstein, MD*

* Department of Pediatrics
{ddagger} Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California
§ Central Institute for the Deaf, Washington University, St Louis, Missouri

--> Objective. To evaluate the growth and neurodevelopmental outcome of 18 surviving Stanford patients who received heart transplantations before their second birthday.

Methods. We compared the growth and neurodevelopmental outcome of these 18 patients with a second group of age-matched comparison patients who underwent other heart surgery requiring cardiopulmonary bypass.

Results. Difficulties with growth and development were more common in the transplant group as were neurologic abnormalities. Speech and language delays as well as hearing problems were also more common in the transplant group.

Conclusion. Multicenter prospective longitudinal neurodevelopmental outcome studies of infant heart transplant patients should be conducted to provide a more efficient basis for evaluating management protocols and assessment of long-term outcomes and of the need for early intervention services.

Key Words: infant heart transplantation • neurodevelopmental outcome

Abbreviations: BSID, Bayley Scales of Infant Development • MDI, Mental Developmental Index • PDI, Psychomotor Developmental Index • SD, standard deviation • SB, Stanford Binet • SICD, Sequenced Inventory of Communication Development • PPVT, Peabody Picture Vocabulary Test • CELF, Clinical Evaluation of Language Fundamentals • TOLD, Test of Language Development

Received for publication Sep 2, 1999; Accepted Jul 20, 2001.




This article has been cited by other articles:


Home page
 Diabetes CareHome page
P. A. Gaudieri, R. Chen, T. F. Greer, and C. S. Holmes
Cognitive Function in Children With Type 1 Diabetes: A meta-analysis
Diabetes Care, September 1, 2008; 31(9): 1892 - 1897.
[Abstract] [Full Text] [PDF]

Home page
 J Pediatr PsycholHome page
J. M. Naguib, E. Kulinskaya, C. L. Lomax, and M. E. Garralda
Neuro-cognitive Performance in Children with Type 1 Diabetes--A Meta-analysis
J. Pediatr. Psychol., July 17, 2008; (2008) jsn074v1.
[Abstract] [Full Text] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
J. L. Wei, M. S. Mayo, H. J. Smith, M. Reese, and R. A. Weatherly
Improved Behavior and Sleep After Adenotonsillectomy in Children With Sleep-Disordered Breathing
Arch Otolaryngol Head Neck Surg, October 1, 2007; 133(10): 974 - 979.
[Abstract] [Full Text] [PDF]

Home page
 Psychiatr. Serv.Home page
J. P. Morrissey, H. J. Steadman, K. M. Dalton, A. Cuellar, P. Stiles, and G. S. Cuddeback
Medicaid Enrollment and Mental Health Service Use Following Release of Jail Detainees With Severe Mental Illness
Psychiatr Serv, June 1, 2006; 57(6): 809 - 815.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
R. Lydic
Sleep disruption is related to allelic variation in the ob gene
Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2006; 290(4): R892 - R893.
[Full Text] [PDF]

Home page
 J Pediatr PsycholHome page
M. Vollrath and M. A. Landolt
Personality Predicts Quality of Life in Pediatric Patients with Unintentional Injuries: A 1-Year Follow-up Study
J. Pediatr. Psychol., September 1, 2005; 30(6): 481 - 491.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
M. L. Wolraich, C. J. Wibbelsman, T. E. Brown, S. W. Evans, E. M. Gotlieb, J. R. Knight, E. C. Ross, H. H. Shubiner, E. H. Wender, and T. Wilens
Attention-Deficit/Hyperactivity Disorder Among Adolescents: A Review of the Diagnosis, Treatment, and Clinical Implications
Pediatrics, June 1, 2005; 115(6): 1734 - 1746.
[Abstract] [Full Text] [PDF]

Home page
 J. Epidemiol. Community HealthHome page
C. Cohet, S. Cheng, C. MacDonald, M. Baker, S. Foliaki, N. Huntington, J. Douwes, and N. Pearce
Infections, medication use, and the prevalence of symptoms of asthma, rhinitis, and eczema in childhood
J. Epidemiol. Community Health, October 1, 2004; 58(10): 852 - 857.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
J. Wray and R. Radley-Smith
Developmental and Behavioral Status of Infants and Young Children Awaiting Heart or Heart-Lung Transplantation
Pediatrics, March 1, 2004; 113(3): 488 - 495.
[Abstract] [Full Text] [PDF]

Home page
 SEMIN CARDIOTHORAC VASC ANESTHHome page
W. C. Oliver Jr
Overview of Heparin and Protamine Management and Dosing Regimens in Pediatric Cardiac Surgical Patients
Seminars in Cardiothoracic and Vascular Anesthesia, December 1, 2003; 7(4): 387 - 410.
[Abstract] [PDF]

Home page
 PediatricsHome page
T. K. McInerny, J. R. Meurer, and C. Lannon
Incorporating Quality Improvement Into Pediatric Practice Management
Pediatrics, November 1, 2003; 112(5): 1163 - 1165.
[Full Text] [PDF]

Home page
 J. Nutr.Home page
J. A. Rivera, C. Hotz, T. Gonzalez-Cossio, L. Neufeld, and A. Garcia-Guerra
The Effect of Micronutrient Deficiencies on Child Growth: A Review of Results from Community-Based Supplementation Trials
J. Nutr., November 1, 2003; 133(11): 4010S - 4020.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
G. S. Marquis, M. E. Penny, J. P. Zimmer, J. M. Diaz, and R. M. Marin
An Overlap of Breastfeeding during Late Pregnancy Is Associated with Subsequent Changes in Colostrum Composition and Morbidity Rates among Peruvian Infants and Their Mothers
J. Nutr., August 1, 2003; 133(8): 2585 - 2591.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
A. M. Haqq, D. D. Stadler, R. H. Jackson, R. G. Rosenfeld, J. Q. Purnell, and S. H. LaFranchi
Effects of Growth Hormone on Pulmonary Function, Sleep Quality, Behavior, Cognition, Growth Velocity, Body Composition, and Resting Energy Expenditure in Prader-Willi Syndrome
J. Clin. Endocrinol. Metab., May 1, 2003; 88(5): 2206 - 2212.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
E. D. Boudreaux, S. D. Emond, S. Clark, and C. A. Camargo Jr
Race/Ethnicity and Asthma Among Children Presenting to the Emergency Department: Differences in Disease Severity and Management
Pediatrics, May 1, 2003; 111(5): e615 - 621.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child.Home page
L B Dahl, P Hasvold, E Arild, T Hasvold, C Wren, L B Dahl, P Hasvold, E Arild, and T Hasvold
Heart murmurs recorded by a sensor based electronic stethoscope and e-mailed for remote assessment
Arch. Dis. Child., October 1, 2002; 87(4): 297 - 301.
[Abstract] [Full Text] [PDF]

Home page
 J Law Med EthicsHome page
J. Folkman
The Podium
J. Law Med. Ethics, September 1, 2002; 30(3): 361 - 366.
[PDF]