PEDIATRICS Vol. 108 No. 1 July 2001, p. e1
Received Sep 18, 2000; accepted Feb 8, 2000.
From the University of Pittsburgh School of Medicine,
Children's Hospital of Pittsburgh, and Western Psychiatric Institute
and Clinic, Pittsburgh, Pennsylvania.
Objective. To determine whether
medically unexplained recurrent abdominal pain (RAP) in childhood
predicts abdominal pain, irritable bowel syndrome (IBS), other somatic
complaints, and psychiatric symptoms and disorders in young
adulthood.
Methods. A sample of 28 young adults evaluated for RAP
between the ages of 6 and 17 years were compared with 28 individually
matched former childhood participants in a study of tonsillectomy and adenoidectomy. RAP caseness was established by structured retrospective chart review requiring agreement by 2 independent reviewers.
Standardized assessments of abdominal pain, IBS, other somatic
symptoms, psychopathology, perceived health, and history of
maltreatment were performed an average of 11.1 years after the index
visit.
Results. Former RAP patients were significantly more
likely than controls to endorse anxiety symptoms and disorders,
hypochondriacal beliefs, greater perceived susceptibility to physical
impairment, poorer social functioning, current treatment with
psychoactive medication, and generalized anxiety in first degree
relatives. There were trends suggesting associations between childhood
RAP and lifetime psychiatric disorder, depression, migraine, and family history of depression, but group differences on abdominal pain, IBS,
other somatic symptoms, and history of maltreatment were not
statistically significant.
Conclusions. There is a strong and relatively specific
association between childhood RAP and anxiety in young adulthood.
Affected children may be at special risk to perceive physical symptoms
as threatening, and should be evaluated for psychiatric disorder on
initial presentation.
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