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PEDIATRICS Vol. 107 No. 1 January 2001, p. e14

ELECTRONIC ARTICLE:
Successful Treatment of Antiepileptic Drug Hypersensitivity Syndrome With Intravenous Immune Globulin

Received Apr 2, 2000; accepted Aug 17, 2000.

Oded Scheuerman*, Yehuda Nofech-Moses*, Avinoam Rachmel*, Dagger , parallel , and Shai Ashkenazi*, §, parallel

From the * Department of Pediatrics A and Units of Dagger  Clinical Pharmacology and § Infectious Diseases, Schneider Children's Medical Center of Israel, Petah Tiqva, and parallel  Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Intravenous immune globulin (IVIG) has proved beneficial for severe immunologically related cutaneous adverse reactions. We report a child with severe antiepileptic drug hypersensitivity syndrome who was successfully treated with IVIG. IVIG should be considered in the pharmacologic armamentarium of severe antiepileptic drug hypersensitivity syndrome. antiepileptic drugs, hypersensitivity, immune globulin.

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