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PEDIATRICS Vol. 107 No. 1 January 2001, pp. 172-173

EXPERIENCE AND REASON:
Severe Ethylene Glycol Ingestion Treated Without Hemodialysis

Received Jan 3, 2000; accepted Mar 31, 2000.

Edward W. Boyer*

Mauricio MejiaDagger

Alan Woolf*

Michael Shannon*

* Children's Hospital Boston, MA 02155 Dagger  University of Colorado School of Medicine Denver, CO 80262

Fomepizole (4-methylpyrazole, Antizol) is being increasingly used in the treatment of ethylene glycol toxicity in adults. Little experience exists with this drug, however, in the pediatric population. We present a case of ethylene glycol poisoning in a child where use of fomepizole averted intravenous ethanol infusion and hemodialysis, limited the duration of intensive care monitoring, and decreased the overall cost of treatment.

 Key words:  4-methylpyrazole, fomepizole, Antizole, ethylene glycol, pediatric.




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