This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Reeves, G. D.
Right arrow Articles by Mackenzie, W. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Reeves, G. D.
Right arrow Articles by Mackenzie, W. G.
Related Collections
Right arrow Therapeutics & Toxicology

PEDIATRICS Vol. 106 No. 6 December 2000, pp. 1484-1488

EXPERIENCE AND REASON:
Vitamin D-Deficiency Rickets in Adopted Children From the Former Soviet Union: An Uncommon Problem With Unusual Clinical and Biochemical Features

Received Feb 29, 2000; accepted Apr 24, 2000.

Grafton D. Reeves*

Steven BachrachDagger

Thomas O. Carpenter§

William G. Mackenzieparallel

* Division of Endocrinology Dagger  Division of General Pediatrics and parallel  Department of Orthopaedics Alfred I. duPont Hospital for Children Wilmington, DE 19899 § Department of Pediatrics (Endocrinology) Yale University School of Medicine New Haven, CT 06504

Rickets is an unusual disorder in international adoptees. Three international adoptees from the former Soviet Union recently presented with rickets. Their clinical and laboratory presentations were atypical, reflecting circumstances unique to children adopted from orphanages in the former Soviet Union and the early initiation of vitamin D therapy. In these children, radiographs of the long bones were diagnostic when the classically diagnostic biochemical parameters, calcium and 25OHD3 levels, were normal.

 Key words:  rickets, vitamin D deficiency, adopted.