PEDIATRICS Vol. 106 No. 5 November 2000, p. e60
Received Jan 20, 2000; accepted Jun 7, 2000.
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From the * Children's Hospital, Winnipeg, Canada;
Children's Hospital Medical Center, Cincinnati, Ohio; § East
Tennessee Children's Hospital, Knoxville, Tennessee; and
Children's Mercy Hospital, Kansas City, Missouri.
Objectives. To determine the association of clear urine by visual inspection with the absence of significant bacteruria, and to compare it with standard urinalysis.
Methods. The study was performed in the emergency
department of Children's Hospital Medical Center, Cincinnati, Ohio. It
was a prospective, convenience sample of children <21 years of age who
had catheterized or midstream clean-catch urine specimen collected for
culture. Clinical findings including the presence or absence of fever, abdominal pain, dysuria, frequency, and urgency were collected for each
patient. Urine was visually assessed for clarity by 2 independent
observers using a standardized technique. Standard laboratory
urinalysis and microscopy were also performed on all specimens. A
positive urine culture was defined as
104 colony-forming
unit (CFU)/mL of a urinary pathogen if obtained by catheterization and
105 CFU/mL if obtained by midstream.
Results. Samples were obtained from 159 patients ranging in age from 4 weeks to 19 years. Females comprised 77% of the patients. One hundred ten of the samples (69%) were clear to visual inspection. There were a total of 29 positive cultures; however, 3 were in children with clear urine. The finding of clear urine on visual inspection had a negative predictive value of 97.3%. These results were similar to those obtained with standard urinalysis.
Conclusion. Clear urine on visual inspection cannot completely eliminate the possibility that a child has a urinary tract infection. However, it is a reproducible test that offers the advantages of being simple, fast, and inexpensive. The finding of clear urine should be considered a reasonable and relatively effective bedside screen for the presence of a urinary tract infection. Key words: urinary tract infection, child, urine clarity, urinalysis, diagnosis.
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