This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Herschel, M.
Right arrow Articles by Lass, N. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Herschel, M.
Right arrow Articles by Lass, N. A.
Related Collections
Right arrow Therapeutics & Toxicology
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

PEDIATRICS Vol. 106 No. 4 October 2000, pp. 831-834

EXPERIENCE AND REASON:
Role of Naloxone in Newborn Resuscitation

Received Oct 28, 1999; accepted Feb 8, 2000.

Marguerite Herschel*

Babak Khoshnood*, §

Nancy A. LassDagger

* Department of Pediatrics Dagger  Committee on Clinical Pharmacology University of Chicago Pritzker School of Medicine and the § Irving B. Harris Graduate School of Public Policy Studies University of Chicago Chicago, IL 60637

Objective.  Because of questions about the basis for the use of naloxone in resuscitation of the newborn, we wished to evaluate the use of naloxone at our institution and an affiliated hospital.

Methodology.  Evaluation of the actual use of naloxone at a university hospital and a community hospital: we document naloxone use by daily survey for a month in one; in the other, we perform a retrospective record review of 1 year's use.

Results.  The university hospital had 240 births during February, 1998. Naloxone was given twice: once, 7 minutes before delivery to a woman at term who had received opiates about 2 hours previously; and once, intramuscularly, to a premature infant for apnea, before being intubated. The community hospital had 2044 births during fiscal 1998. Twenty-six neonates were identified as having received naloxone. Of the 26, 13 received naloxone without needing ventilatory support; all 13 with respiratory depression had a predisposing perinatal complication.

Conclusion.  The use of naloxone in practice may not conform to the American Academy of Pediatrics' guidelines for use in resuscitation of the newborn. The use of naloxone in resuscitation of the newborn should be reevaluated.  Key words:  naloxone, resuscitation, newborn, opiates.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Pharmacol. Rev.Home page
J. Fichna, A. Janecka, J. Costentin, and J.-C. Do Rego
The Endomorphin System and Its Evolving Neurophysiological Role
Pharmacol. Rev., March 1, 2007; 59(1): 88 - 123.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
Part 10.2: Toxicology in ECC
Circulation, December 13, 2005; 112(24_suppl): IV-126 - IV-132.
[Full Text] [PDF]

Home page
 NeoReviewsHome page
W. E. Benitz and M. L. Druzin
Drugs That Affect Neonatal Resuscitation
NeoReviews, April 1, 2005; 6(4): e189 - e195.
[Full Text] [PDF]

Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
W McGuire and P W Fowlie
Naloxone for narcotic exposed newborn infants: systematic review
Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2003; 88(4): F308 - F311.
[Abstract] [Full Text] [PDF]