This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Biederman, J.
Right arrow Articles by Feighner, J. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Biederman, J.
Right arrow Articles by Feighner, J. A.
Related Collections
Right arrow Adolescent Medicine

PEDIATRICS Vol. 106 No. 4 October 2000, pp. 792-797

Patterns of Alcohol and Drug Use in Adolescents Can Be Predicted by Parental Substance Use Disorders

Received Aug 19, 1999; accepted May 19, 2000.

Joseph Biederman*, §, Stephen V. Faraone*, Dagger , §, Michael C. Monuteaux*, parallel , and Jennifer A. Feighner*

From the * Pediatric Psychopharmacology Unit, Massachusetts General Hospital; Dagger  Harvard Institute of Psychiatric Epidemiology and Genetics; § Harvard School of Medicine; and parallel  Harvard School of Public Health, Boston, Massachusetts.

Objective.  To examine the specificity of risk for alcohol or drug abuse or dependence (substance use disorders [SUDs]) in offspring exposed to particular subtypes of parental SUDs.

Methods.  The original sample was derived from 2 groups of index children: 140 attention-deficit/hyperactivity disorder (ADHD) probands and 120 non-ADHD comparison probands. These groups had 174 and 129 biological siblings and 279 and 240 parents, respectively.

Results.  Independent of familial risk, exposure to parental SUDs predicted SUDs in the offspring. Controlling for duration of exposure, we found that adolescence was a critical developmental period for exposure to parental SUDs. Because all our analyses controlled for social class, ADHD status, and parental lifetime history of SUDs, these results show that exposure to parental SUDs predicts offspring SUDs independently of these risk factors.

Conclusions.  These results support the critical importance of familial environmental risk factors for the development of SUDs in youth in general and particularly in those at high risk for these disorders. These results highlight adolescence as a critical period for the deleterious effects of exposure to parental SUDs, supporting the need to develop preventive and early intervention strategies targeted at adolescents at high risk for SUDs.  Key words:  substance use, adolescent, exposure, critical period.




This article has been cited by other articles:


Home page
 Scand J Public HealthHome page
U. Kemppainen, K. Tossavainen, E. Vartiainen, V. Jokela, P. Puska, V. Pantelejev, and M. Uhanov
Environmental factors as predictors of alcohol use among ninth-grade adolescents in Pitkaranta (Russian Karelia) and in eastern Finland
Scand J Public Health, September 1, 2008; 36(7): 769 - 777.
[Abstract] [PDF]

Home page
 J Pediatr PsycholHome page
W. K. K. Lam, J. D. Cance, A. N. Eke, D. H. Fishbein, S. R. Hawkins, and J. Cassie Williams
Children of African-American Mothers Who Use Crack Cocaine: Parenting Influences on Youth Substance Use
J. Pediatr. Psychol., September 1, 2007; 32(8): 877 - 887.
[Abstract] [Full Text] [PDF]

Home page
 Am J EpidemiolHome page
M. R. Hayatbakhsh, R. Alati, D. M. Hutchinson, K. Jamrozik, J. M. Najman, A. A. Mamun, M. O'Callaghan, and W. Bor
Association of Maternal Smoking and Alcohol Consumption with Young Adults' Cannabis Use: A Prospective Study
Am. J. Epidemiol., September 1, 2007; 166(5): 592 - 598.
[Abstract] [Full Text] [PDF]

Home page
 Br. J. PsychiatryHome page
S. S. F. GAU, M.-Y. CHONG, P. YANG, C.-F. YEN, K.-Y. LIANG, and A. T. A. CHENG
Psychiatric and psychosocial predictors of substance use disorders among adolescents: Longitudinal study
The British Journal of Psychiatry, January 1, 2007; 190(1): 42 - 48.
[Abstract] [Full Text] [PDF]

Home page
 J PsychopharmacolHome page
T. E. Wilens and J. Biederman
Alcohol, drugs, and attention-deficit/ hyperactivity disorder: a model for the study of addictions in youth
J Psychopharmacol, July 1, 2006; 20(4): 580 - 588.
[Abstract] [PDF]

Home page
 Int J EpidemiolHome page
M. R Hayatbakhsh, J. M Najman, K. Jamrozik, A. A Mamun, G. M Williams, and R. Alati
Changes in maternal marital status are associated with young adults' cannabis use: evidence from a 21-year follow-up of a birth cohort
Int. J. Epidemiol., June 1, 2006; 35(3): 673 - 679.
[Abstract] [Full Text] [PDF]