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Varicella-Zoster Infections

PEDIATRICS Vol. 106 No. 2 August 2000, p. e28

ELECTRONIC ARTICLE:
Chickenpox Attributable to a Vaccine Virus Contracted From a Vaccinee With Zoster

Received Sep 24, 1999; accepted Mar 17, 2000.

Philip Alfred Brunell and Takele Argaw

From Ahmanson Pediatrics Department, Cedars Sinai Medical Center, Los Angeles, California; and the Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

Five months after 2 siblings were immunized with varicella vaccine, 1 developed zoster. Two weeks later the second sibling got a mild case of chicken pox. Virus isolated from the latter was found to be vaccine type. Thus, the vaccine strain was transmitted from the vaccinee with zoster to his sibling. Vaccinees who later develop zoster must be considered contagious. varicella-zoster, zoster, vaccine, transmission, rash, PstI.

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