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Kawasaki Disease (Mucocutaneous...
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PEDIATRICS Vol. 105 No. 5 May 2000, p. e64

ELECTRONIC ARTICLE:
Ticlopidine Plus Aspirin for Coronary Thrombosis in Kawasaki Disease

Received Sep 28, 1999; accepted Dec 13, 1999.

Maureen O'Brien*, §, Ira A. Parnessparallel , Ellis J. NeufeldDagger , §, Annette L. Baker*, §, Robert P. Sundel*, §, and Jane W. Newburger*, §

From the Departments of * Cardiology and Dagger  Medicine, Children's Hospital, and § Department of Pediatrics, Harvard Medical School, Boston, Massachusetts; and parallel  Department of Pediatrics, Mount Sinai Hospital and Mount Sinai School of Medicine, New York, New York.

Selective inhibitors of the adenosine 5'-diphosphate pathway of platelet activation have been used rarely in children in the United States. We report the successful use of ticlopidine, together with aspirin, in a 7-month-old infant with Kawasaki disease complicated by a thrombus in a giant coronary aneurysm that failed to resolve with thrombolytic therapy. Kawasaki disease, coronary aneurysms, antithrombotic therapy, ticlopidine, children.

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