This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mullins, M. E.
Right arrow Articles by Daya, M. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mullins, M. E.
Right arrow Articles by Daya, M. R.
Related Collections
Right arrow Therapeutics & Toxicology
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

PEDIATRICS Vol. 105 No. 2 February 2000, pp. 402-404

Unintentional Pediatric Superwarfarin Exposures: Do We Really Need a Prothrombin Time?

Received Feb 2, 1999; accepted Jun 18, 1999.

Michael E. Mullins, Christina L. Brands, and Mohamud R. Daya

From the Oregon Poison Center, Department of Emergency Medicine, Oregon Health Sciences Center, Portland, Oregon.

Objective.  To determine whether routine follow-up coagulation studies are useful in children with accidental exposures to rodenticides containing superwarfarin compounds.

Design.  Retrospective review of poison center charts involving pediatric superwarfarin exposures occurring in two 2-year periods.

Setting.  An American Association of Poison Control Centers-certified regional poison control center with an annual call volume of 55 000 calls per year from a 2-state area with a combined population of 4 million people.

Outcome Measures.  Prothrombin times and/or international normalized ratios and reported clinical signs of excessive anticoagulation after exposure.

Results.  Of 542 children in 4 years of data collection, follow-up prothrombin times and/or international normalized ratios measurements did not detect any significant coagulation abnormalities. No child developed bleeding complications. No child required or received antidotal treatment with vitamin K.

Conclusion.  Normal preschool-aged children with unintentional acute exposures to superwarfarin rodenticides do not require any routine follow-up laboratory studies and do not require any medical intervention.  Key words:  poisoning, children, anticoagulant, rodenticide.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 NEJMHome page
M. Laposata, E. M. Van Cott, and M. H. Lev
Case 1-2007 -- A 40-Year-Old Woman with Epistaxis, Hematemesis, and Altered Mental Status
N. Engl. J. Med., January 11, 2007; 356(2): 174 - 182.
[Full Text] [PDF]

Home page
 Emerg. Med. J.Home page
A V Ramanan, P Gissen, and B Bose-Haider
Intentional overdose of warfarin in an adolescent: need for follow up
Emerg. Med. J., January 1, 2002; 19(1): 90 - 90.
[Full Text] [PDF]

Home page
 JWatch Emergency Med.Home page
Is Prothrombin Time Necessary After Rat Poison Ingestion?
Journal Watch Emergency Medicine, May 1, 2000; 2000(501): 19 - 19.
[Full Text]