This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bruckner, A. L.
Right arrow Articles by Morelli, J. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bruckner, A. L.
Right arrow Articles by Morelli, J. G.
Related Collections
Right arrow Infectious Disease & Immunity
Right arrow Allergy & Dermatology
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

PEDIATRICS Vol. 105 No. 1 January 2000, p. e3

ELECTRONIC ARTICLE:
Does Sensitization to Contact Allergens Begin in Infancy?

Received Apr 26, 1999; accepted Jul 7, 1999.

Anna L. Bruckner*, William L. Weston*, and Joseph G. Morelli*

From the Departments of * Pediatrics and Dermatology, University of Colorado Health Sciences Center, Denver, Colorado.

Objective.  Because previous studies have found allergic contact sensitization common in children by 5 years of age, our aim was to determine the prevalence of positive epicutaneous test results in children <5 years of age and to determine whether sensitization to contact allergens was as common in infancy.

Methods.  We recruited 95 asymptomatic children 6 months to 5 years of age from well-child visits at Denver area pediatric practices for epicutaneous patch testing using the T.R.U.E. Test system. Allergens were placed on the skin for 48 hours, and at a later follow-up visit, positive reactions were evaluated.

Results.  A total of 85 patients completed the study. Of these, 20 (24.5%) had 1 or more positive reactions to the tested allergens. Positive reactors ranged from 6 to 65.5 months of age, with an average of 30.4 months of age. Of the children, 16 reacted to 1 allergen, and 4 reacted to 2. Eleven positive reactions were observed to nickel, followed by 8 to thimerosal. Other positive reactions were to neomycin, cobalt, and kathon CG.

Conclusions.  Children as young as 6 months of age may be sensitized to contact allergens. Within this pediatric population, the prevalence of sensitization is 24.5%. Sensitization to contact allergens may occur in infants.  Key words:  allergic contact dermatitis, allergic contact sensitization, epicutaneous testing, infants, young children.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Arch DermatolHome page
K. A. Zug, D. McGinley-Smith, E. M. Warshaw, J. S. Taylor, R. L. Rietschel, H. I. Maibach, D. V. Belsito, J. F. Fowler Jr, F. J. Storrs, V. A. DeLeo, et al.
Contact Allergy in Children Referred for Patch Testing: North American Contact Dermatitis Group Data, 2001-2004
Arch Dermatol, October 1, 2008; 144(10): 1329 - 1336.
[Abstract] [Full Text] [PDF]