PEDIATRICS Vol. 103 No. 1 January 1999, pp. 100-106
Received Mar 3, 1998; accepted Jul 22, 1998.
, and
From the * Children's Memorial Medical Center, Northwestern
University, Chicago, Illinois; and the
Illinois Department of Public
Health, Springfield, Illinois.
Objective. Beginning in 1995, Illinois law permitted targeted
as opposed to universal
blood lead
screening in low-risk areas, which were defined by ZIP code
characteristics. State guidelines recommended specific lead risk
assessment questions to use when targeting screening. This study was
designed to evaluate the sensitivity and specificity of Illinois lead
risk assessment questions.
Design. Parents bringing their 9- or 10- or 12-month and
24-month-old children for health supervision visits at 13 pediatric
practices and parents of children (aged 6 through 25 months and who
needed a blood lead test) receiving care at 5 local health departments completed a lead risk assessment questionnaire concerning their child.
Children had venous or capillary blood lead testing. Venous confirmation results of children with a capillary level
10 µg/dL were used in analyses.
Children. There were 460 children with both blood and questionnaire data recruited at the pediatric practices (58% of eligible) and 285 children (51% of eligible) recruited at local health departments. Of the 745 children studied, 738 provided a ZIP code that allowed their residence to be categorized as in a low-risk (n = 456) or high-risk (n = 282) area.
Results. Sixteen children (3.5%) living in low-risk areas
versus 34 children (12.1%) living in high-risk areas had a venous
blood lead level (BLL)
10 µg/dL; 1.8% and 5.3%,
respectively, had a venous BLL
15 µg/dL. For children living in
low-risk areas, Illinois mandated risk assessment questions (concerning
ever resided in home built before 1960, exposure to renovation, and
exposure to adult with a job or hobby involving lead) had a combined
sensitivity of .75 for levels
10 µg/dL and .88 for levels
15
µg/dL; specificity was .39 and .39, respectively. The sensitivity of
these questions was similar among children from high-risk areas;
specificity decreased to .27 and .28, for BLLs
10 µg/dL and
15
µg/dL, respectively. The combination of items requiring respondents
to list house age (built before 1950 considered high risk) and indicate
exposure to renovation had a sensitivity among children from low-risk
areas of .62 for BLLs
10 µg/dL with specificity of .57; sensitivity and specificity among high-risk area children were .82 and .36, respectively. For this strategy, similar sensitivities and
specificities for low and high-risk areas were found for BLLs
15
µg/dL.
Conclusions. The Illinois lead risk assessment questions identified most children with an elevated BLL. Using these questions, the majority of Illinois children in low-risk areas will continue to need a blood lead test. This first example of a statewide screening strategy using ZIP code risk designation and risk assessment questions will need further refinement to limit numbers of children tested. In the interim, this strategy is a logical next step after universal screening. Key words: blood lead level, blood lead screening.
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