This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hoyme, H. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hoyme, H. E.
Related Collections
Right arrow Office Practice
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Facebook   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

PEDIATRICS Vol. 102 No. 1 Supplement July 1998, pp. 247-249

COMMENTARY:
Antenatal Detection of Hereditary Disorders, by Henry L. Nadler, MD, Pediatrics, 1968;42:912-918

Received Mar 19, 1998; accepted Mar 19, 1998.

Comments by H. Eugene Hoyme

From the Division of Medical Genetics, Department of Pediatrics, Stanford University School of Medicine, Stanford, California.

Amniotic fluid cells obtained by transabdominal amniocentesis at various stages of pregnancy were cultivated successfully. The intrauterine detection of Down syndrome, galactosemia, and mucopolysaccharidosis was established using the cultivated amniotic fluid cells. The use of this procedure increases the precision of genetic counseling and should stimulate the development of new approaches for the intrauterine management of genetic defects. However, until considerably more experience is gained with these techniques, the procedures should be considered experimental.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Facebook Facebook   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?