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PEDIATRICS Vol. 101 No. 1 January 1998, pp. 82-85

Evaluation of a Diagnostic Approach to Pediatric Interstitial Lung Disease

Received Feb 19, 1997; accepted May 15, 1997.

Leland L. Fan*, Claudia A. KozinetzDagger , Robin R. Deterding§, and Susan M. Brugman§, parallel

From the * Pediatric Pulmonary Section and Dagger  Academic General Pediatric Section, Department of Pediatrics, Baylor College of Medicine, Houston, Texas; the § Pediatric Pulmonary Section, Department of Pediatrics, University of Colorado Health Sciences Center, and parallel  National Jewish Medical and Research Center, Denver, Colorado.

Objective.  To evaluate the value of a systematic approach to the diagnosis of pediatric interstitial lung disease (ILD).

Methods.  In this descriptive, observational, prospective study, we evaluated 51 children presenting with ILD of unknown etiology during a 3-year period. Specific clinical information regarding history, physical examination, diagnostic evaluation, and final diagnosis was recorded on each patient.

Results.  A specific diagnosis was established by history and physical examination alone in 1 patient, noninvasive tests alone in 8 others, and invasive tests, including lung biopsy, in another 26. Of the remaining patients, 8 had a suggestive diagnosis, and 8 had no specific diagnosis.

Conclusions.  A systematic approach to the diagnosis of pediatric ILD is useful, and not all patients need lung biopsy for diagnosis.

Key words: interstitial lung disease, pulmonary fibrosis, children.




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