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PEDIATRICS Vol. 100 No. 2 August 1997, p. e10
Copyright ©1997 by the American Academy of Pediatrics

ELECTRONIC ARTICLE:
Auxiliary Liver Transplant in Fulminant Failure

Received Jan 17, 1997; accepted Apr 1, 1997.

Philip Rosenthal, John P. Roberts, Nancy L. Ascher, and John C. Emond

Pediatric Liver Transplant Program University of California, San Francisco Medical Center San Francisco, CA 94143

Fulminant hepatic failure (FHF) is defined as a syndrome of acute liver failure with the development of hepatic encephalopathy and severe hypoprothrombinemia occurring within 2 months of the onset of symptoms or jaundice in a person without preexisting liver disease. Total orthotopic liver transplantation (OLTX) is a lifesaving therapeutic option for patients with FHF, but currently requires lifelong immunosuppression to maintain the graft. Auxiliary partial orthotopic liver transplantation (A-OLTX) is a procedure whereby only a portion of the native liver is removed, and the remainder of the native liver is left in situ. A-OLTX provides temporary support until the native liver recovers and immunosuppression can be withdrawn.

We describe the successful application of emergency A-OLTX in a young girl who accidentally ingested Amanita phalloides mushrooms and developed FHF.

Key words: auxiliary liver transplant, fulminant hepatic failure, emergency, Amanita phalloides.




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