PEDIATRICS Vol. 10 No. 1 July 1952, pp. 28-32
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EXPERIMENTAL USE OF METHYL TESTOSTERONE AND TESTOSTERONE IN PREMATURE INFANTS

HORST A. AGERTY M.D.1 and JOSEPH N. SEITCHIK M.D.2

1 The Division of Pediatrics, Hahnemann Medical College, Philadelphia.
2 The Division of Women, Hahnemann Medical College, Philadelphia.

One hundred premature infants weighing between 1.8 and 2.3 kg. were studied in respect to time to regain birth weight, time to gain to 2.5 kg., rate of weight gain and protein-nitrogen intake. Fifty-five received an androgen either orally or parenterally. The infants received a diet of varying protein content.

While the results suggested a minimal protein-anabolic effect in all the treated infants, this was associated with a decreased nitrogen intake. Thus no clinical benefit resulted.

Neither the method of administration of the androgen nor the protein content of the diet offered influenced the results.

Submitted on February 19, 1952


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