PEDIATRICS Vol. 1 No. 3 March 1948, pp. 337-345
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USE OF MESOXALYL UREA (ALLOXAN) IN TREATMENT OF AN INFANT WITH CONVULSIONS DUE TO IDIOPATHIC HYPOGLYCEMIA

NATHAN B. TALBOT M.D.1, JOHN D. CRAWFORD M.D.1, and C. CABELL BAILEY M.D.1

1 The Department of Pediatrics, Harvard Medical School, The Children's Medical Service, Massachusetts General Hospital and the George F. Baker Clinic, New England Deaconess Hospital, Boston.

The case history of an eight-month-old infant with severe convulsions due to idiopathic hypoglycemia is described. Because of the poor prognosis and lack of other certain means of therapy, treatment of the hypoglycemia by means of mesoxalyl urea was undertaken with apparent success.

It is concluded that mesoxalyl urea, though a potentially dangerous drug, may be worthy of further cautious trial in patients of the type described here.

Submitted on November 8, 1947