TABLE 2 Association Between Parental Psychiatric Disorders and Children's Autism Diagnosis: Adjusted ORs and 95% CIs
| Disorder |
Maternal Diagnoses Among
|
Paternal Diagnoses Among
|
| Autism Case Subjects, n |
Control Subjects, n |
OR (95% CI)a |
Autism Case Subjects, n |
Control Subjects, n |
OR (95% CI)a |
|
| Schizophrenia |
7 |
55 |
1.9 (0.8–4.7) |
8 |
61 |
2.1 (0.9–4.9) |
| Other nonaffective psychoses |
13 |
174 |
1.1 (0.6–2.1) |
11 |
126 |
1.2 (0.6–2.5) |
| Affective disorders |
42 |
631 |
1.2 (0.8–1.7) |
28 |
480 |
1.0 (0.6–1.5) |
| Not including depression |
20 |
392 |
1.1 (0.8–1.4) |
21 |
293 |
1.2 (0.7–2.0) |
| Only depression |
22 |
239 |
1.7 (1.0–2.6) |
7 |
187 |
0.6 (0.3–1.4) |
| Neurotic and personality disorders and other non psychotic disorders |
68 |
882 |
1.7 (1.3–2.2) |
44 |
756 |
1.0 (0.6–1.5) |
| Alcohol and drug addiction or abuse |
31 |
478 |
1.1 (0.8–1.7) |
58 |
953 |
1.2 (0.8–1.9) |
| Autism |
1 |
5 |
2.3 (0.3–20.5) |
— |
— |
— |
|
— indicates category comprised too few individuals for analysis.
a Data were adjusted for child's age, gender, and hospital of birth and parents’ ages at delivery, country of birth, socioeconomic status, other psychiatric disorders of the parent under analysis, and any psychiatric disorder among the opposite parent.